1956
DOI: 10.1001/jama.1956.02970120029009
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Meningeal Diverticula of Sacral Nerve Roots (Perineurial Cysts)

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Cited by 68 publications
(27 citation statements)
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“…The proposed etiologies for the perineural cysts include ischaemic degeneration, inflammation, hemorrhage, trauma, arachnoid proliferation, obstruction of perineural lymphatic flow or developmental origin [1,3,[8][9][10][11]. Several authors have proposed that increased CSF hydrostatic pressure may be a factor in the origin of perineural cysts or their growth and becoming symptomatic [4,12,13]. The patient in this study had a history of heavy lifting at work-maneuver that raises CSF pressure.…”
Section: Introductionmentioning
confidence: 84%
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“…The proposed etiologies for the perineural cysts include ischaemic degeneration, inflammation, hemorrhage, trauma, arachnoid proliferation, obstruction of perineural lymphatic flow or developmental origin [1,3,[8][9][10][11]. Several authors have proposed that increased CSF hydrostatic pressure may be a factor in the origin of perineural cysts or their growth and becoming symptomatic [4,12,13]. The patient in this study had a history of heavy lifting at work-maneuver that raises CSF pressure.…”
Section: Introductionmentioning
confidence: 84%
“…Various studies indicate that women develop symptomatic perineural cysts more often than men [9,10,13]. MRI is considered as the gold standard for diagnosis and is more sensitive than CT myelography [14,15].…”
Section: Introductionmentioning
confidence: 99%
“…On the contrary, most surgeons, including ourselves, consider the cysts to be a congenital arachnoidal defect. 1,[12][13][14][15] A postulated mechanism involves a potential or very small "ball-valve" communication (also called "traffic pore") between the congenital pouch (the cyst) and the subarachnoid space, by which CSF can flow into the pouch but not exit. Therefore, the cysts can enlarge progressively because of continuous 1-way infusion of CSF.…”
Section: Discussionmentioning
confidence: 99%
“…This theory, however, does not explain the occurrence of arachnoid cysts ventral to the spinal cord [4, 6]. Strully [7] hypothesized that arachnoid cysts formed due to the presence of areas of lower resistance in the arachnoid, which may be dilated by the continued stress caused by the normal daily variations in CSF hydrodynamics. Fortuna and Mercuri [8] suggested that arachnoid granulations become trapped in various locations and cyst formation results from CSF production and sequestration along the path of resistance.…”
Section: Discussionmentioning
confidence: 99%