Ménière's Symptom Complex: Medical Treatment

Furstenberg, A. C.; Lashmet, F. H.; Lathrop, Frank D.

doi:10.1177/000348949210100109

Cited by 23 publications

(23 citation statements)

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“…Anecdotally, some patients have described acute symptoms after high salt exposure, and treatment protocols based on sodium restriction have been a foundation of the management of MD since the 1930s. 16 Recent evidence has suggested that the effects of sodium on endolymphatic hydrops are far more complex than mere fluctuations in endolymphatic levels. 17 Experimental data from both animals and humans have shown that a low-sodium diet results in nearly no change in plasma sodium levels.…”

Section: Lifestyle Adjustmentmentioning

confidence: 99%

Medical Management Of Ménière's Disease

Coelho

Lalwani

2008

The Laryngoscope

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Section: Lifestyle Adjustmentmentioning

confidence: 99%

Medical Management Of Ménière's Disease

Coelho

Lalwani

2008

The Laryngoscope

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“…5 Medical therapy aimed at decreasing endolymph volume (low-sodium diet, diuretic use) is the standard initial treatment. 6,7 None of the current medical or surgical treatments can be expected to improve hearing. The lack of a specific, nondestruc- tive method to control vertigo and possibly restore hearing has stimulated continuing research.…”

mentioning

confidence: 99%

The Effects of Transtympanic Micropressure Treatment in People With Unilateral Ménière's Disease

Gates

Green²,

Tucci

et al. 2004

Arch Otolaryngol Head Neck Surg

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To evaluate the efficacy of a portable lowintensity alternating pressure generator, the Meniett device, in controlling the symptoms of Mé niè re's disease.Design: A randomized, placebo-controlled, doubleblind, multicenter clinical trial of 4 months' duration.Setting: Four study sites: 3 academic medical centers and 1 private practice.Patients: Sixty-seven people aged 33 to 71 years with established, active, unilateral cochleovestibular Ménière's disease randomly assigned to a treatment or control group. Five cases were excluded (2 dropouts, 3 protocol violations), leaving 62 evaluable cases. I n t e r v e n t i o n :The Meniett device was selfadministered 3 times daily. The placebo Meniett device was identical but exerted no pressure. All participants had a tympanostomy tube inserted in the affected ear.Main Outcome Measures: Participants rated vertigo and activity each day on a symptom report card. Hearing tests, electrocochleography, and questionnaires were completed at baseline, 2 months, and 4 months. Results:The treatment group experienced significantly less severe vertigo, fewer days with definitive vertigo, and fewer days lost from work (sick days) during the follow-up period than did the control group. Hearing and electrocochleographic results did not differ between the groups. Outcomes did not differ by age, gender, laterality, or duration of symptoms. Outcomes were affected by vestibular loss and baseline level of vertigo. The tympanostomy tube had no short-term effect on vertigo symptoms. There were no complications from using the Meniett device. Conclusion:The Meniett device is a minimally invasive, safe, and efficacious intermediate treatment for people with substantial vertigo uncontrolled by medical therapy.

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“…Studies on the increase of sodium levels inducing hydrops attacks have been performed since then, with numerous related publications [3]. More recent studies also suggest that the restriction of salt, associated with the use of diuretics, gets better symptom control in patients with Meniere's disease [4].…”

Section: Salt Restriction and Other Dietary Modificationsmentioning

confidence: 99%