Meniere's disease

Harcourt, Jonny; Barraclough, Kevin; Bronstein, Adolfo M.

doi:10.1136/bmj.g6544

Cited by 81 publications

(60 citation statements)

References 15 publications

(10 reference statements)

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“…32 Definitions and Diagnostic Criteria (Differentiation from TIA 1 Approach to Initial Diagnosis) MD is characterized by recurrent attacks of spontaneous vertigo associated with hearing loss and tinnitus in the same ear. 34 Aural fullness and headache can be found during the attacks. The International Classification for Vestibular Disorders Committee of the Barany Society has developed consensus diagnostic criteria with American Academy of Otolaryngology -Head and Neck Surgery, European Academy of Otology & Neuro-Otology, Japan Society for Equilibrium Research, and the Korean Balance Society.…”

Section: Prevalence and Pathophysiologic Mechanismsmentioning

confidence: 98%

“…50,51 In patients in whom there is significant audiovestibular loss in the affected ear but with continuing severe attacks, subablative therapy with intratympanic gentamicin may be effective in curtailing attacks. 34 Finally, the role of vestibular rehabilitation in the acute phase of the disease is controversial, given the fluctuating nature of vestibular symptoms in these patients. Nevertheless, there is evidence to suggest that vestibular rehabilitation across the spectrum of MD improves both subjective and objective balance function.…”

Section: Triage and Dispositionmentioning

confidence: 99%

“…46 Various interventions are used to reduce the number of attacks or progression of audiovestibular failure in MD, although none have a strong evidence base. 34 One intervention is dietary salt restriction (daily sodium intake of <2 g/d), which is thought to reduce the osmotic build-up of pressure in the endolymphatic compartment. Using Acute Vertigo -Vestibular Migraine and Mé niè re's a similar logic, diuretics are also prescribed for MD, although a Cochrane review did not support their use.…”

Section: Triage and Dispositionmentioning

confidence: 99%

See 2 more Smart Citations

Early Diagnosis and Management of Acute Vertigo from Vestibular Migraine and Ménière's Disease

2015

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Section: Prevalence and Pathophysiologic Mechanismsmentioning

confidence: 98%

Section: Triage and Dispositionmentioning

confidence: 99%

Section: Triage and Dispositionmentioning

confidence: 99%

See 1 more Smart Citation

Early Diagnosis and Management of Acute Vertigo from Vestibular Migraine and Ménière's Disease

2015

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“…We further could not exclude Cogan syndrome, Tullio phenomenon, or otoliths since no Read codes exist for these conditions either. Many lifestyle factors, such as dietary habits or physical activity, as well as some suspected risk factors for MD, such as caffeine, chocolate, and cheese consumption, are not recorded in the CPRD [Harcourt et al, 2014;Herrett et al, 2015].…”

Section: Discussionmentioning

confidence: 99%

Population-Based Study on the Epidemiology of Ménière's Disease

et al. 2017

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Background and Objective: Ménière's disease (MD) is a disorder of the inner ear typically showing recurrent acute episodes of vertigo, hearing loss, and tinnitus. Epidemiologic studies on MD are scarce. We assessed the incidence rates (IRs) of MD and describe the characteristics of MD cases, comparing them to control patients without recorded evidence of MD. Study Design: We conducted a retrospective population-based follow-up study and a nested case-control analysis using data from the UK-based Clinical Practice Research Datalink. Methods: We identified patients between 18 and 79 years of age with an incident MD diagnosis between January 1993 and December 2014. We assessed the IRs of betahistine-treated MD. In the nested case-control analysis, we matched 4 controls to each MD case on sex, age, general practice, years of active history in the database, and calendar time. We conducted a χ² test to present p values in order to compare the prevalence of demographics, comorbidities, and co-medication between cases and controls. Results: We identified 5,508 MD cases and 22,032 MD-free controls (65.4% females). The overall IR for MD in the UK was 13.1 per 100,000 person-years. More cases were female, and the mean age at diagnosis was 55.4 ± 13.7 years. Smoking and alcohol consumption were less prevalent among MD cases. Depression, other affective disorders, sleeping disorders, anxiety, and migraine were more prevalent among MD cases than among controls. Conclusions: MD is uncommon in primary care in the UK with a preponderance among females.

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“…Vertigo attacks are accompanied by hearing loss, tinnitus, and fullness in the pathological ear [1][2][3] . Vertigo is the major symptoms and their effect on balance function is a key concern for patients, which may affect their daily functions negatively.…”

Section: Introductionmentioning

confidence: 99%

The Reliability and Validity of “Dokuz Eylül University Meniere’s Disease Disability Scale”

et al. 2018

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OBJECTIVE:Ménière's Disease (MD) is a chronic, non-life threatening inner ear disease, with attacks of disabling vertigo, progressive hearing loss, and tinnitus as the major symptoms. All three symptoms, separately or in combination, cause great distress and have a considerable impact on the quality of life of the patients. The aims of this study were to develop a disease-specific quality of life survey for patients with MD and to analyze the relationships between the audiovestibular findings and the survey. MATERIALS and METHODS:Following Ear-Nose-Throat examination and audiovestibular tests, the Dokuz Eylül University Meniere's Disease Disability Scale (DEU-MDDS) and Turkish version of the Dizziness Handicap Inventory (DHI-T) were administered to 93 patients with definite MD. Reliability and validity analyses of the scale were performed. RESULTS:There were 45 (48.4%) male and 48 (51.6%) female patients and the mean age was 48.9±12.1 years. Cronbach's alpha was 0.92 and intraclass correlation coefficients of the DEU-MMDS were significant (p<0.001). Results of the Goodness of Fit Statistics showed that the expression levels of the items were high and the correlation coefficients of each item with the scale were sufficient. There was a statistically significant correlation between DHI-T scores and MDDS. DEU-MDDS was not related to the vestibular tests, age or gender (p>0.05). CONCLUSION:The MDDS is a valid and reliable scale as a disease-specific quality of life questionnaire for patients with MD.

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Meniere's disease

Cited by 81 publications

References 15 publications

Early Diagnosis and Management of Acute Vertigo from Vestibular Migraine and Ménière's Disease

Early Diagnosis and Management of Acute Vertigo from Vestibular Migraine and Ménière's Disease

Population-Based Study on the Epidemiology of Ménière's Disease

The Reliability and Validity of “Dokuz Eylül University Meniere’s Disease Disability Scale”

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