Menetrier’s Disease

Frank, Barry W.; Kern, Fred

doi:10.1016/s0016-5085(19)34136-8

Cited by 32 publications

(6 citation statements)

References 23 publications

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“…The gastroscopic and radiological appearances are indistinguishable from infiltrating carcinoma or lymphoma (Bockus, 1963;Jones et al, 1968) and in this case the diagnosis was only established after the stomach had been removed. Spontaneous regression has been reported (Grime and Whitehead, 1951;Frank and Kern, 1967), but the severity of blood loss in this patient clearly justified total gastrectomy.…”

mentioning

confidence: 72%

Diffuse hypertrophy of gastric mucosa (Menetrier's disease) and iron-deficiency anaemia

Singh¹,

Cumaraswamy²,

Corrin³

1969

Gut

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SUMMARY A 23-year-old woman presented with intractable iron-deficiency anaemia. A barium meal showed widespread mucosal abnormalities in the stomach and massive mucosal hypertrophy was found at laparotomy. Repeated tests for occult blood were negative but gastrointestinal haemorrhage was confirmed by isotopic blood labelling. In the face of persistent anaemia and radiological progression, total gastrectomy was performed, since when a normal blood picture has been maintained. The excised stomach showed hyperplasia of all the mucosal elements, minimal inflammation, and no obvious bleeding point. Blood loss was attributed to diapedesis from a greatly increased capillary network.

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mentioning

confidence: 72%

Diffuse hypertrophy of gastric mucosa (Menetrier's disease) and iron-deficiency anaemia

Singh¹,

Cumaraswamy²,

Corrin³

1969

Gut

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“…Initially, as in case 1 or in mild cases of MCnetrier's disease, conservative treatment with repeated small meals and antacids may relieve the symptoms of dyspepsia (7). However, most cases such as ours are not diagnosed before marked symptoms and signs have appeared, such as severe pains, bleeding and edema with hypoproteinemia.…”

Section: Most Of the Dark Tubular Cells Are Mucoid Metaplastic Cellsmentioning

confidence: 92%

“…However, mixed forms of Menttrier's disease, gastric polyposis and HHG may occur (3, 17). It has been suggested that the classical Menetrier's disease might represent a "burned out" phase of HHG (7).…”

Section: Con-mentioning

confidence: 99%

“…We agree with the opinion that intestinal metaplasia should not be considered an important feature in this disease (14). Progression and conversion of Menttrier's disease to gastric atrophy with intestinal metaplasia have, however, been described (7).…”

Section: Con-mentioning

confidence: 99%

“…The disease may be combined with adenomas of endocrine glands (11,19). More recently autoimmunity has been discussed as a cause of Menetrier's disease (7). The patients may suffer from dyspepsia or be free from symptoms, but as a result of protein loss in the stomach hypoproteinemia with edema may occur.…”

mentioning

confidence: 99%

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Clinical and Morphological Studies of Giant Hypertrophic Gastritis (Ménétrier's Disease)

Raotma

Angervall

Dahl

et al. 1974

Journal of Internal Medicine

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Abstract. The authors describe four cases of giant hypertrophic gastritis (Ménétrier's disease), which demonstrate that the disease is easily overlooked clinically. In all four cases the definite diagnosis was established after morphological examination of the surgical specimens. The importance of gastroscopy, gastric secretory studies, studies of the protein metabolism and X‐ray investigation of the upper gastrointestinal tract for the clinical diagnosis is emphasized, even if a definite diagnosis seems possible only after examination of full‐thickness surgical biopsy specimens.

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