Mendelian randomization study highlights hypothyroidism as a causal determinant of alopecia areata
Xue-Yong Zheng,
Yan-Ping Ma,
Bo Zhang
et al.
Abstract:BackgroundAlthough observational studies have found an association between hypothyroidism and alopecia areata, the causality of this relationship remains unclear.ObjectivesThis study aimed to investigate the genetic variants associated with hypothyroidism and their potential impact on the risk of developing alopecia areata.Methodsgenome-wide association study summary statistics for hypothyroidism (30,155 cases and 379,986 controls) and alopecia areata (289 cases and 211,139 controls) were obtained from the IE… Show more
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