Mendelian Randomization Analysis of Systemic Iron Status and Risk of Different Types of Kidney Disease
Jiahui Zhou,
Wanting Shi,
Dongya Wu
et al.
Abstract:With rapid increases in incidence, diverse subtypes, and complicated etiologies, kidney disease remains a global public health problem. Iron, as an essential trace element, has pleiotropic effects on renal function and the progression of kidney diseases. A two-sample Mendelian randomization (MR) analysis was implemented to determine the potential causal effects between systemic iron status on different kidney diseases. Systemic iron status was represented by four iron-related biomarkers: serum iron, ferritin, … Show more
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