Mendelian randomization analysis of 34,497 German Holstein cows to infer causal associations between milk production and health traits
Helen Schneider,
Valentin Haas,
Ana-Marija Krizanac
et al.
Abstract:Background
Claw diseases and mastitis represent the most important health issues in dairy cattle with a frequently mentioned connection to milk production. Although many studies have aimed at investigating this connection in more detail by estimating genetic correlations, they do not provide information about causality. An alternative is to carry out Mendelian randomization (MR) studies using genetic variants to investigate the effect of an exposure on an outcome trait mediated by genetic varia… Show more
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