Men Who Have Sex With Men in Kisumu, Kenya: Comfort in Accessing Health Services and Willingness to Participate in HIV Prevention Studies

Okall, Dancun O.; Ondenge, Ken; Nyambura, Monicah; Otieno, Fredrick; Hardnett, Felicia; Turner, Kyle; Mills, Lisa; Masinya, Kennedy; Chen, Robert T.; Gust, Deborah A.

doi:10.1080/00918369.2014.951261

Cited by 33 publications

(39 citation statements)

References 15 publications

(26 reference statements)

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“…The gaining of knowledge through research participation was mentioned 16 times overall, ranked in the top three reasons four times, and was given as the top reason in one paper to participate . Knowledge was ranked fifth in Sub‐Saharan Africa and Eastern Europe, in HIV research, by male and patient participants and for hypothetical studies.…”

Section: Resultsmentioning

confidence: 99%

The willingness to participate in biomedical research involving human beings in low‐ and middle‐income countries: a systematic review

Browne

Rees

Delden

et al. 2019

Tropical Med Int Health

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ObjectivesTo systematically review reasons for the willingness to participate in biomedical human subjects research in low‐ and middle‐income countries (LMICs).MethodsFive databases were systematically searched for articles published between 2000 and 2017 containing the domain of ‘human subjects research’ in ‘LMICs’ and determinant ‘reasons for (non)participation’. Reasons mentioned were extracted, ranked and results narratively described.ResultsNinety‐four articles were included, 44 qualitative and 50 mixed‐methods studies. Altruism, personal health benefits, access to health care, monetary benefit, knowledge, social support and trust were the most important reasons for participation. Primary reasons for non‐participation were safety concerns, inconvenience, stigmatisation, lack of social support, confidentiality concerns, physical pain, efficacy concerns and distrust. Stigmatisation was a major concern in relation to HIV research. Reasons were similar across different regions, gender, non‐patient or patient participants and real or hypothetical study designs.ConclusionsAddressing factors that affect (non‐)participation in the planning process and during the conduct of research may enhance voluntary consent to participation and reduce barriers for potential participants.

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Section: Resultsmentioning

confidence: 99%

The willingness to participate in biomedical research involving human beings in low‐ and middle‐income countries: a systematic review

Browne

Rees

Delden

et al. 2019

Tropical Med Int Health

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“…Homosexuality was decriminalized in South Africa over 20 years ago, but is still unlawful in Kenya [16, 17]. A survey among MSM in Kisumu, Kenya reported that 60% were uncomfortable seeking care in a public hospital [18]. That survey reported a high willingness of MSM to be contacted for participation in future HIV research studies.…”

Section: Discussionmentioning

confidence: 99%

“…That survey reported a high willingness of MSM to be contacted for participation in future HIV research studies. However, in-depth interviews revealed that the main reason for not wanting to participate was fear of personal information being shared outside of the study [18]. …”

Section: Discussionmentioning

confidence: 99%

Accuracy of Self-Reported HIV Status Among African Men and Transgender Women Who Have Sex with Men Who were Screened for Participation in a Research Study: HPTN 075

et al. 2018

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Some HIV-infected individuals in research studies may choose not to disclose knowledge of their HIV status to study staff. We evaluated the accuracy of self-reported HIV status among African men and transgender women who have sex with men and who were screened for a research study. Sixty-seven of 183 HIV-infected participants reported a prior HIV diagnosis. Samples from the remaining 116 participants were tested for antiretroviral (ARV) drugs. Thirty-six of the 116 participants had ARV drugs detected, indicating that they were on antiretroviral treatment; these participants were classified as previously diagnosed based on ARV drug testing. Among participants classified as previously diagnosed, disclosure of a prior HIV diagnosis varied among study sites (p = 0.006) and was more common among those who reported having sex with men only (p = 0.002). ARV drug testing in addition to self-report improves the accuracy for identifying individuals with a prior HIV diagnosis.

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“…As a result, they have poor access to care and may lack trust in providers [11,12]. In a small cohort on the Kenya coast, we found that MSM struggled with antiretroviral therapy (ART) adherence and had worse clinical outcomes compared with other high-risk individuals, including female sex workers and men with multiple sex partners [13].…”

Section: Introductionmentioning

confidence: 99%

Development and pilot testing of an intervention to promote care engagement and adherence among HIV-positive Kenyan MSM

Graham¹,

Micheni

Kombo

et al. 2015

Aids

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Objectives In many African settings, MSM are a stigmatized group whose access to and engagement in HIV care may be challenging. Our aim was to design a targeted, culturally appropriate intervention to promote care engagement and antiretroviral therapy (ART) adherence for MSM in coastal Kenya, and describe intervention safety, feasibility, and acceptability based upon a small pilot study. Design Based on qualitative work including in-depth interviews with HIV-positive MSM and focus groups with providers, we developed a tailored intervention and conducted a pilot test to refine intervention materials and procedures. Methods The Shikamana intervention combines modified Next-Step Counseling by trained providers, support from a trained peer navigator, and tailored use of SMS messaging, phone calls, and discrete pill carriers. Providers, including counselors and clinicians, work together with peer navigators as a case management team. Results Forty HIV-positive MSM aged 19–51 participated in intervention development and testing. Six counselors, three clinical officers, and four MSM peers were trained in intervention procedures. Of 10 ART-naïve participants who enrolled in the pilot, eight completed follow-up with no adverse events reported. One participant was lost to follow-up after 2 months and another failed to initiate ART despite ongoing counseling. No adverse events were reported. Staff feedback and exit interviews rated the intervention as feasible and acceptable. Conclusion This adherence support intervention tailored for Kenyan MSM was well tolerated, feasible, and acceptable in the pilot phase. A randomized controlled trial of a scaled-up programme to estimate intervention efficacy is ongoing.

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Men Who Have Sex With Men in Kisumu, Kenya: Comfort in Accessing Health Services and Willingness to Participate in HIV Prevention Studies

Cited by 33 publications

References 15 publications

The willingness to participate in biomedical research involving human beings in low‐ and middle‐income countries: a systematic review

The willingness to participate in biomedical research involving human beings in low‐ and middle‐income countries: a systematic review

Accuracy of Self-Reported HIV Status Among African Men and Transgender Women Who Have Sex with Men Who were Screened for Participation in a Research Study: HPTN 075

Development and pilot testing of an intervention to promote care engagement and adherence among HIV-positive Kenyan MSM

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