Memory performance of patients with major depression in an everyday life situation

Beblo, Thomas; Kater, Leona; Baetge, Sharon Jean; Drießen, Martin; Piefke, Martina

doi:10.1016/j.psychres.2016.12.013

Cited by 24 publications

(9 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…literature in depression showing a lack of association between objective and subjective measure of cognition (e.g. Beblo, Kater, Baetge, Driessen, & Piefke, 2017;Moritz, Ferahli, & Naber, 2004;Petersen, Porter, & Miskowiak, 2019). Nevertheless, participants did experience some improvement as demonstrated by their levels of personal goals achieved: only one participant did not reach at least one WM and inhibition-related goal.…”

Section: Discussionmentioning

confidence: 86%

A pilot study of cognitive remediation in remitted major depressive disorder patients

Hammar

Semkovska

Borgen

et al. 2020

Applied Neuropsychology: Adult

View full text Add to dashboard Cite

Major depressive disorder (MDD) is associated with working memory (WM) impairments. These deficits often persist following remission and are associated with rumination, a recognized risk factor for depression relapse. The efficacy of WM-targeted cognitive remediation as a potential relapse prevention tool has not been investigated. The present pilot study aimed to investigate the feasibility, acceptability, and cognitive benefits of a WM-targeted cognitive remediation program in remitted depression. Twenty-eight MDD participants in remission were recruited. The intervention consisted of twenty-five 30-40-minute training sessions, coupled with weekly coaching, administered over a 5-week period. Before and after the intervention, a battery of objective neuropsychological tests and self-report measures was administered. Key outcomes were WM, inhibition and rumination. Acceptability of the intervention was observed, with 83% showing high motivation, along with WM gains for all completers (n ¼ 18, 64% of recruited participants). The cognitive remediation selectively improved targeted WM functions, as measured by objective tests. This did not translate into self-reported improvements in everyday WM or inhibition. However, all but one completer achieved at least one personal goal related to WM and 44% achieved two or, the maximum possible, three such goals. For remitters whose WM was significantly enhanced after the intervention, the cognitive remediation also decreased dysphoric-mood related rumination. The successful pilot testing of the WM-targeted intervention supports the conduct of a fully powered randomized controlled trial as a relapse prevention approach in remitted MDD.

show abstract

Section: Discussionmentioning

confidence: 86%

A pilot study of cognitive remediation in remitted major depressive disorder patients

Hammar

Semkovska

Borgen

et al. 2020

Applied Neuropsychology: Adult

View full text Add to dashboard Cite

show abstract

“…It thus needs to be further investigated whether there may exist a general relationship between high intelligence and the risk of depression and/or anxiety in patients with breast cancer. Future studies have to take into consideration that modulating factors besides intelligence may contribute to the inconsistent pattern of published data concerning this issue [26][27][28].…”

Section: Intelligencementioning

confidence: 99%

Anxiety and depression in patients with breast cancer undergoing radiotherapy: the role of intelligence, life history, and social support—preliminary results from a monocentric analysis

et al. 2022

Self Cite

View full text Add to dashboard Cite

Purpose It is known that the diagnosis of breast cancer often causes anxiety and depression. Radiotherapy of the breast as an obligatory part of a breast-conserving treatment concept can markedly increase these psychological symptoms in many, but not all patients. In this clinical observational study, we aimed at identifying cognitive, health-related and social factors that may either enhance or reduce the emergence of anxiety and depression. Methods Using a longitudinal study design with 25 women (mean age: 52.9 years; SD = 10.6; age range 29–70 years) with a first diagnosis of nonmetastatic breast cancer, measures of anxiety, depression, situational emotional states, intelligence, and aspects of social frameworks were assessed before, during, and after radiotherapy of the breast. At 4 time-points, standard and self-constructed questionnaires were used to assess the course of anxiety and depressive symptoms across the radiotherapy intervention. Results We found that anxiety is highest immediately before the start of radiation therapy, while the anxiety level was lowest on the day that therapy was completed. Anxiety and depression were enhanced in women with a lifetime history of chronic diseases at all time points of measurement. Moreover, women with high intelligence and low social support had stronger symptoms of depression than women with low intelligence and a stable family background at some time points of measurement. The degree of anxiety was neither related to intelligence nor to social support. Conclusion For the first time, we demonstrate empirical pilot data on cognitive and social modulators of anxiety and depression in women with breast cancer over the course of radiotherapy. Our results may help to optimize clinical procedures and thereby reduce symptoms of anxiety and depression in these patients.

show abstract

“…We were primarily interested in examining whether the subjective changes associated with memory, attention, and executive functions would be predicted by demographic, clinical, or neurobiological measures. In cognitively unimpaired individuals, there could be education and gender effects in the perception of cognitive decline; a patient's age or mood could also modulate subjective deficits 7–9 . In patients with MCI, however, the individual weight of these predictors may change.…”

Section: Introductionmentioning

confidence: 99%

Predictors of subjective cognitive deficits in patients with mild cognitive impairment

et al. 2021

View full text Add to dashboard Cite

Background Detailed examination of cognitive deficits in patients with mild cognitive impairment (MCI) yields substantial diagnostic and prognostic value, specifically with respect to memory. Magnitude and characteristics of subjective cognitive deficits, however, often receive less attention in this population at risk for developing dementia. Methods We investigated predictors of subjective cognitive deficits in patients with MCI, using a detailed assessment for such impairments associated with different cognitive domains, as well as demographic and clinical variables including magnetic resonance imaging data. Results The strongest predictor for subjective memory deficits was depressed mood, whereas subjective performance issues associated with attention or executive functions also corresponded to measurable impairments in the respective cognitive domains. Reduced hippocampal thickness and hemispheric entorhinal cortex thickness asymmetry were associated with objective memory impairment but not with subjective deficits or symptoms of depression. Conclusions Whereas low objective memory performance and reduced cortical thickness within medial temporal lobe subregions could be associated with neurodegeneration, greater subjective memory deficits in patients with MCI may indicate psychological burden.

show abstract

Memory performance of patients with major depression in an everyday life situation

Cited by 24 publications

References 27 publications

A pilot study of cognitive remediation in remitted major depressive disorder patients

A pilot study of cognitive remediation in remitted major depressive disorder patients

Anxiety and depression in patients with breast cancer undergoing radiotherapy: the role of intelligence, life history, and social support—preliminary results from a monocentric analysis

Predictors of subjective cognitive deficits in patients with mild cognitive impairment

Contact Info

Product

Resources

About