Memory outcome 2 years after anterior temporal lobectomy in patients with drug-resistant epilepsy

Abstract

Our results suggest that the long-term memory outcome of TLE patients undergoing ATL without invasive presurgical assessment may be good in most cases not only for right-sided but also for left-sided resections.

The corpus callosum and recovery of working memory after epilepsy surgery

“…However, findings of verbal memory decline following epilepsy surgery vary. Although decline in delayed memory is commonly reported after left anterior temporal lobe resection, memory stability or a gradual return to presurgical level of memory functioning is also reported . This variability suggests the need to identify predictive factors.…”

“…Although decline in delayed memory is commonly reported after left anterior temporal lobe resection, [38][39][40] memory stability or a gradual return to presurgical level of memory functioning is also reported. 41,42 This variability suggests the need to identify predictive factors. Although our findings did not support CC area as a potential explanatory factor for DR-change, other "brain reserve" factors such as the structural and functional integrity of the ipsilateral hemisphere should continue to be explored.…”

Evaluación de la memoria en la epilepsia del lóbulo temporal para predecir sus cambios tras la cirugía. Una revisión sistemática

“…En 2 de ellos 13,35 , los test efectuados de modo prequirúrgico son predictivos de los cambios postoperatorios de la memoria en todo el tiempo de seguimiento, mientras que en el estudio restante no se encuentra una relación significativa 26 . Este último estudio, con seguimiento a 2 años, también difiere de los anteriores en que reporta datos de mejoría de la memoria a largo plazo, mientras que los otros muestran un deterioro, si bien se estima que el cambio de la memoria es dinámico, y en los primeros 2 años puede existir mejoría o estabilidad respecto a la primera medida posquirúrgica, especialmente en los pacientes con cirugía derecha, para luego sufrir un deterioro progresivo 35 .…”

Cognitive Outcome after Surgery in Patients with Mesial Temporal Lobe Epilepsy

“…Anterior temporal lobectomy (ATL) or selective amygdalohippocampectomy (SAH) is a surgical procedure used to treat intractable temporal lobe epilepsy (TLE) (3). Many groups have reported significantly improved seizure outcome in approximately 60-90% of surgically treated patients (4,5,6,7,8). However, seizure frequency alone after surgery is insufficient to decide whether a patient is in a satisfactory condition, and concerns have been expressed regarding neuropsychological outcomes after surgery (6,9).…”

“…Many groups have reported significantly improved seizure outcome in approximately 60-90% of surgically treated patients (4,5,6,7,8). However, seizure frequency alone after surgery is insufficient to decide whether a patient is in a satisfactory condition, and concerns have been expressed regarding neuropsychological outcomes after surgery (6,9). Impairments of various cognitive functions, such as verbal memory, visual memory, naming, verbal fluency, and attention, have been reported after left-and right-sided surgeries (10).…”