Memory of Childhood Sexual Abuse Among Clinicians: Characteristics, Outcomes, and Current Therapy Attitudes

Little, Liza; Hamby, Sherry

doi:10.1177/107906320101300402

Cited by 2 publications

(2 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The childhood exposure to violence scale contained 34 questions that asked participants to respond to circumstances that might have happened during their childhood from birth through age 18. The response options were “1 time,” “2 times,” “3 times,” “4 times,” “5 times or more,” “no times,” and “prefer not to answer.” This scale has a test-retest reliability coefficient of 0.90 and Cronbach’s α= 0.85 ( Finkelhor et al., 2010 , 2015 ; Stith and Hamby, 2002 ; Little and Hamby, 2001 ). Community exposure to violence as adults was measured by 35 items.…”

Section: Methodsmentioning

confidence: 99%

DNA methylation and exposure to violence among African American young adult males

Saadatmand

Gurdziel

Jackson

et al. 2021

Brain, Behavior, & Immunity - Health

View full text Add to dashboard Cite

Exposure to violence (ETV) has been linked to epigenomics mechanisms such as DNA methylation (DNAm). We used epigenetic profiling of blood collected from 32 African American young adult males who lived in Washington DC to determine if changes in DNAm at CpG sites affiliated with nervous and immune system were associated with exposure to violence. Pathway analysis of differentially methylated regions comparing high and low ETV groups revealed an enrichment of gene sets annotated to nervous system and immune ontologies. Many of these genes are known to interact with each other which suggests DNAm alters gene function in the nervous and immune system in response to ETV. Using data from a unique age group, young African American adult males, we provide evidence that lifetime ETV could impact DNA methylation in genes impacted at Central Nervous System and Immune Function sites. Method Methylation analysis was performed on DNA collected from the blood of participants classified with either high or low lifetime ETV. Illumina®MethylationEPIC Beadchips (~850k CpG sites) were processed on the iScan System to examine whole-genome methylation differences. Differentially methylated CpG-sites between high (n = 19) and low (n = 13) groups were identified using linear regression with violence and substance abuse as model covariates. Gene ontology analysis was used to identify enrichment categories from probes annotated to the nearest gene. Results A total of 595 probes (279 hypermethylated; 316 hypomethylated) annotated to 383 genes were considered differentially methylated in association with ETV. Males with high ETV showed elevated methylation in several signaling pathways but were most impacted at Central Nervous System and Immune Function affiliated sites. Eight candidate genes were identified that play important biological roles in stress response to violence with HDAC4 (10%), NR4A3 (11%), NR4A2 (12%), DSCAML1(12%), and ELAVL3 (13%) exhibiting higher levels in the low ETV group and DLGAP1 (10%), SHANK2 (10%), and NRG1(11%) having increased methylation in the high ETV group. These findings suggest that individuals subjected to high ETV may be at risk for poor health outcomes that have not been reported previously.

show abstract

Section: Methodsmentioning

confidence: 99%

DNA methylation and exposure to violence among African American young adult males

Saadatmand

Gurdziel

Jackson

et al. 2021

Brain, Behavior, & Immunity - Health

View full text Add to dashboard Cite

show abstract

“…This article is not the first to suggest that clinicians' countertransference can influence outcomes for patients (Flaherty and Sege 2005;Little and Hamby 2001). Specifically, research on informed consent suggests that clinicians' feelings and attitudes can influence their considerations of patients' decision-making capacity (Ganzini, et al 2004, 140).…”

Section: An Introduction To Psychodynamicsmentioning

confidence: 95%

Legalism, Countertransference, and Clinical Moral Perception

Rentmeester

George²

2009

The American Journal of Bioethics

View full text Add to dashboard Cite

This target article focuses on dynamics that arise in three typical ethically complex cases in which psychiatric consultations are requested by physicians: a dying patient refuses life-prolonging treatment, an uncooperative patient demands to be allowed to go outside and smoke, and an angry patient demands to be admitted to the hospital. The discussion canvasses what is at stake morally and clinically in each of these cases and explores clinician-patient interactions, dynamics in relationships between consulting physicians and consultant psychiatrists, patient transference, and physician countertransference. The article defines legalism and countertransference and argues that an ethically and clinically important consequence of these phenomena for patients is distortion of clinicians' perceptions of patients' decisions and vulnerabilities. The discussion also describes how legalism and countertransference adversely affect how clinicians treat their psychiatrist colleagues. Finally, the article suggests how the effects of legalism and countertransference can be mitigated.

show abstract

Memory of Childhood Sexual Abuse Among Clinicians: Characteristics, Outcomes, and Current Therapy Attitudes

Cited by 2 publications

References 27 publications

DNA methylation and exposure to violence among African American young adult males

DNA methylation and exposure to violence among African American young adult males

Legalism, Countertransference, and Clinical Moral Perception

Contact Info

Product

Resources

About