Memory Complaints in Medically Refractory Epilepsy: Relationship to Epilepsy-Related Factors

Hendriks, M.P.H.; Aldenkamp, Albert P.; Vlugt, H. van der; Alpherts, W.C.J.; Vermeulen, Jan

doi:10.1006/ebeh.2002.0320

Cited by 53 publications

(24 citation statements)

References 8 publications

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“…Most previous reports have suggested subjective memory concerns relate to mood disorders particularly depression or to neuroticism both in the general population [24] and in epilepsy [4], [14], [25]–[27]. We did not find a significant correlation between SM and neuroticism but there was correlation with depression postoperatively.…”

Section: Discussioncontrasting

confidence: 82%

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Subjective Memory Evaluation before and after Temporal Lobe Epilepsy Surgery

et al. 2014

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Subjective memory (SM), a self-evaluation of memory, in contrast to objective memory (OM) measured by neuropsychological testing, is less well studied in patients with epilepsy. We assessed SM before and after temporal lobectomy. The Frequency of Forgetting 10 scale (FOF-10), developed to evaluate SM in dementia, was given before and one year after temporal lobectomy. Reliability and validity for use in epilepsy were first assessed. Measures of depression (CES-D) and neuroticism (PANAS) were done before and after surgery as well as complete neuropsychological assessment of OM. Correlation analysis between FOF-10 results and all the other variables was implemented. In 48 patients the FOF-10 was reliable and valid showing high internal consistency in all items (Cronbach's alpha >0.82) and high reproducibility (p<0.01). The FOF-10 also correlated with the memory assessment clinics self rating scale (MAC-S) (p<0.01). FOF-10 scores improved or were unchanged postoperatively in 28 patients (58%) and worsened in 20 (42%). The FOF-10 did not significantly correlate with memory scores from neuropsychological testing but did correlate with perceived word finding difficulty (p<0.001) and postoperative depression (p<0.05). A reduction in number of antiepileptic drugs (AEDs) after surgery distinguished those with improved postoperative SM. No correlation was found between SM and neuroticism, side of surgery or number of seizures. The FOF-10 is a brief and reliable measure of subjective memory in patients with epilepsy. Perceived memory impairment reflects more emotional state, language problems and quantity of AEDs than actual defects in memory function. These results would potentially be useful in presurgical counselling and management of memory issues after temporal lobe surgery.

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Section: Discussioncontrasting

confidence: 82%

“…In general, those with epilepsy are more likely to report memory problems than is the general population [4]. In the clinic, both the patient's perception as to whether they have a memory problem or not and the results of neuropsychological testing should determine changes in management.…”

Section: Introductionmentioning

confidence: 99%

Subjective Memory Evaluation before and after Temporal Lobe Epilepsy Surgery

et al. 2014

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“…Moreover, patients with long-lasting TLE may show a chronic cognitive deterioration (Hermann et al, 2008(Hermann et al, , 2010. Although perceived cognitive failures inconstantly correspond to objective deficits (Giovagnoli et al, 1997;Hendriks et al, 2002;Ponds and Hendriks, 2006;Helmstaedter and Elger, 2008;Giovagnoli, 2013), both self-rated and neuropsychological impairments may affect quality of life (QoL) (Perrine et al, 1995;Giovagnoli et al, 2014).…”

Section: Why Cognitive Rehabilitation In Epilepsy?mentioning

confidence: 99%

Cognitive rehabilitation in epilepsy: An evidence-based review

Farina¹,

Raglio²,

Giovagnoli³

2015

Epilepsy Research

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“…Subjective cognitive complaints are very common among individuals with epilepsy of all ages [9] and are a significant predictor of poorer self-reported quality of life in this group [10]. However, the degree of subjective complaints is not consistently associated with objective cognitive dysfunction [11].…”

Section: Introductionmentioning

confidence: 99%

“…However, the degree of subjective complaints is not consistently associated with objective cognitive dysfunction [11]. Factors such as older age and higher intelligence level have been associated with greater memory complaints [9] while epilepsy characteristics (e.g., seizure type, frequency, AEDs) are not consistently related to subjective memory complaints among these individuals [9,12]. Depression, which is very common among patients with epilepsy [13,14], has been consistently shown to be related to both subjective cognitive complaints [10,13,[15][16][17][18][19] and objective cognitive function [20] in this group.…”

Section: Introductionmentioning

confidence: 99%