Membrane Technological Pathways and Inherent Structure of Bacterial Cellulose Composites for Drug Delivery

Mensah, Alfred; Chen, Yajun; Narh, Christopher; Wei, Qufu

doi:10.3390/bioengineering9010003

Cited by 14 publications

(6 citation statements)

References 191 publications

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“…A few studies have evidenced the BC as dental canal treatment or oral fields, as it provides absorption, tensile strength expansion, and biological features compared to other paper point materials. The BC maintains excellent absorption and expansion capacity and maintains good mechanical properties under wet conditions [ 93 ].…”

Section: Applicationsmentioning

confidence: 99%

Bacterial Cellulose and Its Applications

Choi

Rao

et al. 2022

Polymers

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The sharp increase in the use of cellulose seems to be in increasing demand in wood; much more research related to sustainable or alternative materials is necessary as a lot of the arable land and natural resources use is unsustainable. In accordance, attention has focused on bacterial cellulose as a new functional material. It possesses a three-dimensional, gelatinous structure consisting of cellulose with mechanical and thermal properties. Moreover, while a plant-originated cellulose is composed of cellulose, hemi-cellulose, and lignin, bacterial cellulose attributable to the composition of a pure cellulose nanofiber mesh spun is not necessary in the elimination of other components. Moreover, due to its hydrophilic nature caused by binding water, consequently being a hydrogel as well as biocompatibility, it has only not only used in medical fields including artificial skin, cartilage, vessel, and wound dressing, but also in delivery; some products have even been commercialized. In addition, it is widely used in various technologies including food, paper, textile, electronic and electrical applications, and is being considered as a highly versatile green material with tremendous potential. However, many efforts have been conducted for the evolution of novel and sophisticated materials with environmental affinity, which accompany the empowerment and enhancement of specific properties. In this review article, we summarized only industry and research status regarding BC and contemplated its potential in the use of BC.

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Section: Applicationsmentioning

confidence: 99%

Bacterial Cellulose and Its Applications

Choi

Rao

et al. 2022

Polymers

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“…Studies on polymers of a natural and artificial origin have demonstrated different drug delivery systems (DDS) ensuring minimal or no side effects. Nanotechnology used jointly with nanomembranes is a novel, promising strategy for DDS [ 177 ]. According to the authors cited, the nanocarriers’ properties responsible for enhancing the efficiency of DDS include biocompatibility, biosafety, encapsulation capacity, molecular polarity, bioavailability, and therapeutic efficiency (controlled distribution and release, cellular absorption, excretion, pharmacokinetics, toxicity and depuration).…”

Section: Bacterial Cellulosementioning

confidence: 99%

Bacterial Cellulose as a Versatile Biomaterial for Wound Dressing Application

et al. 2022

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Chronic ulcers are among the main causes of morbidity and mortality due to the high probability of infection and sepsis and therefore exert a significant impact on public health resources. Numerous types of dressings are used for the treatment of skin ulcers-each with different advantages and disadvantages. Bacterial cellulose (BC) has received enormous interest in the cosmetic, pharmaceutical, and medical fields due to its biological, physical, and mechanical characteristics, which enable the creation of polymer composites and blends with broad applications. In the medical field, BC was at first used in wound dressings, tissue regeneration, and artificial blood vessels. This material is suitable for treating various skin diseases due its considerable fluid retention and medication loading properties. BC membranes are used as a temporary dressing for skin treatments due to their excellent fit to the body, reduction in pain, and acceleration of epithelial regeneration. BC-based composites and blends have been evaluated and synthesized both in vitro and in vivo to create an ideal microenvironment for wound healing. This review describes different methods of producing and handling BC for use in the medical field and highlights the qualities of BC in detail with emphasis on biomedical reports that demonstrate its utility. Moreover, it gives an account of biomedical applications, especially for tissue engineering and wound dressing materials reported until date. This review also includes patents of BC applied as a wound dressing material.

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“…Drug delivery systems refer to the advanced technologies used for targeted delivery and/or controlled release of therapeutic drugs [ 31 ]. In the past few decades, drug delivery systems received much attention, since they offer potential benefits, such as reducing side effects, improving therapeutic effects, and possible reduction of drug doses [ 32 , 259 ]. There are three key factors required in an effective drug delivery system, including drug carriers, drug-loading ratio, and controlled release rate [ 260 ].…”

Section: Bc-based Nanocompositesmentioning

confidence: 99%

“…Due to its unique properties, BC is a promising material for industry and technology [ 18 ]. It has great potential to be used in medicine [ 4 , 19 , 20 , 21 , 22 ] as a biomaterial for tissue engineering [ 20 , 23 , 24 ], wound dressing [ 25 , 26 , 27 , 28 ] and drug delivery systems [ 5 , 29 , 30 , 31 , 32 ], it can be applied in electronics (sensors, energy storage devices, speakers, acoustic membranes) [ 33 ], the environmental industry (water purification, filtration and adsorption techniques) [ 34 , 35 ], and the food industry (artificial food, additives, food packaging [ 36 ]. The relatively large diversity of cellulose-producing microorganisms, as well as a wide variety of cultivation methods, creates an excellent opportunity to modify and adjust the properties of the material and find new areas of its application.…”

Section: Introductionmentioning

confidence: 99%

Bacterial Cellulose-Based Polymer Nanocomposites: A Review

et al. 2022

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Bacterial cellulose (BC) is currently one of the most popular environmentally friendly materials with unique structural and physicochemical properties for obtaining various functional materials for a wide range of applications. In this regard, the literature reporting on bacterial nanocellulose has increased exponentially in the past decade. Currently, extensive investigations aim at promoting the manufacturing of BC-based nanocomposites with other components such as nanoparticles, polymers, and biomolecules, and that will enable to develop of a wide range of materials with advanced and novel functionalities. However, the commercial production of such materials is limited by the high cost and low yield of BC, and the lack of highly efficient industrial production technologies as well. Therefore, the present review aimed at studying the current literature data in the field of highly efficient BC production for the purpose of its further usage to obtain polymer nanocomposites. The review highlights the progress in synthesizing BC-based nanocomposites and their applications in biomedical fields, such as wound healing, drug delivery, tissue engineering. Bacterial nanocellulose-based biosensors and adsorbents were introduced herein.

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Membrane Technological Pathways and Inherent Structure of Bacterial Cellulose Composites for Drug Delivery

Cited by 14 publications

References 191 publications

Bacterial Cellulose and Its Applications

Bacterial Cellulose and Its Applications

Bacterial Cellulose as a Versatile Biomaterial for Wound Dressing Application

Bacterial Cellulose-Based Polymer Nanocomposites: A Review

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