Membrane surface functionalization via theophylline derivative coating and streptavidin immobilization

Hierrezuelo, Jesús; Romero, V.; Benavente, J.; Rico, Rodrigo; López‐Romero, Juan Manuel

doi:10.1016/j.colsurfb.2013.09.007

Cited by 10 publications

(3 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It can be also used to monitorize streptavidin interactions when adsorbed on polymeric support. 33,24 However, by using these polymeric systems, random interaction between theophylline derivative and surfaces were observed.…”

Section: Theophylline Attachment and Protein Adhesion Studymentioning

confidence: 99%

“…For example, theopyllines are methylxanthine derivatives with pharmacological applications, which have been used as templates for the specific incorporation of proteins due its extensively affinity for streptavidin. 24 Here we present the optimization of the covalent grafting of tripod-shaped molecules (compound 1) on alkynyl-modified silicon substrates by CuAAC reaction. In order to define the optimal conditions for silicon surface nanostructuration, we have analyzed in depth the influence of experimental variables as the tripod concentration, reagents and solvents, as well as temperature and shaking during the preparation.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Tripodal penta( p -phenylene) for the biofunctionalization of alkynyl-modified silicon surfaces

Sánchez-Molina

Dı́az

Valpuesta

et al. 2018

Applied Surface Science

Self Cite

View full text Add to dashboard Cite

Section: Theophylline Attachment and Protein Adhesion Studymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Tripodal penta( p -phenylene) for the biofunctionalization of alkynyl-modified silicon surfaces

Sánchez-Molina

Dı́az

Valpuesta

et al. 2018

Applied Surface Science

Self Cite

View full text Add to dashboard Cite

“…We have recently prepared oligo(ethylene glycol)-alkene substituted theophyllines and characterize them upon adsorption in the surface of porous and dense support membranes [16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Study of the self-assembly process of an oligo(ethylene glycol)-thioacetyl substituted theophylline (THEO) on gold substrates

Sánchez-Obrero

Chávez

Madueño

et al. 2018

Journal of Electroanalytical Chemistry

View full text Add to dashboard Cite

Green Tea Makes Polyphenol Nanoparticles with Radical‐Scavenging Activities

Xiang

Yang

Guo

et al. 2017

Macromol. Rapid Commun.

View full text Add to dashboard Cite

lactide, tannin, tea polyphenols (TP), and many others. [5a,6] Among them, TP are of particular interest as monomers for broadening the scope of functional nanomaterials with interesting physicochemical properties and biological activities. [7] TP, also referred as catechins, represent a typical class of polyphenol mixtures directly extracted from green tea. The unique molecular structures (i.e., catechol and pyrogallol units) and biofunctions (i.e., antioxidation and metal chelation) of TP offer ideal scenarios in establishing a series of polymeric nanomaterials with virtually new possibilities for structural and functional variation. [8] For example, Li's group used Cu 2+ to mediate oxidative coupling assembly of TP molecules for the development of porous and hollow nanoparticles as controlled delivery platforms; [8a] Fei et al. reported the rapid one-pot preparation of autofluorescent TP-based core-shell nanocomposites via Ag + oxidation-inducing self-assembly process under microwave irradiation; [8b] Markova et al. employed the oxidationreduction reaction between TP and Fe 3+ to synthesize the TP-Fe nano-hybrids with significant ecotoxicological impact. [8c] Generally speaking, current approaches for the fabrication of polyphenol nanomaterials mainly involve the oxidation of TP building blocks by using foreign metal ion additives. Despite the proliferation of work via similar strategy, all those established methods have met with profound challenges yet to be resolved. Issues including additional toxicity introduced by foreign additives, as well as the spontaneous metal-catechol/pyrogallol complexation process, might hinder the formation of pure organic polyphenol nanomaterials (note that only metal-organic hybrid materials can be obtained by conventional methods). [5b] Therefore, an environmentally friendly synthetic strategy via greener processes is still highly desirable toward functional polyphenol nanoparticles (PNs) without using any foreign toxic additives.To address this issue, herein we employ theophylline, [9] another kind of biomass compound also extracted from green tea leaves, to copolymerize with TP monomers for the construction of pure organic materials in the presence of air (Scheme 1). This one-pot green method provides a facile access to functional PNs with controlled sizes and desired biofunctions. Results and Discussion Synthesis of Polyphenol NanoparticlesIt was anticipated that the TP molecules could undergo oxidation-mediated self-polymerization under alkaline conditions AntioxidantsThe constant demand for functional nanomaterials from natural biomass polymers usually requires new "green" synthetic strategies without using any foreign additives. Here, the green fabrication of a series of polyphenol nanoparticles (PNs) only from green tea extraction compounds is reported (i.e., tea polyphenols and theophylline). It is found that the nanoparticle formation process involves covalent copolymerization of monomers, as well as noncovalent self-assembly pathways. Additionally, the re...

show abstract

Membrane surface functionalization via theophylline derivative coating and streptavidin immobilization

Cited by 10 publications

References 24 publications

Tripodal penta( p -phenylene) for the biofunctionalization of alkynyl-modified silicon surfaces

Tripodal penta( p -phenylene) for the biofunctionalization of alkynyl-modified silicon surfaces

Study of the self-assembly process of an oligo(ethylene glycol)-thioacetyl substituted theophylline (THEO) on gold substrates

Green Tea Makes Polyphenol Nanoparticles with Radical‐Scavenging Activities

Contact Info

Product

Resources

About