Membrane Stabilizing and Thrombolytic Activities of Sida rhombifolia L.

Khan, Mohammd Firoz; Rabbi, Sikder Nahidul Islam; Hossain, Aslam; Rashid, Mohammad A.

doi:10.3329/bpj.v17i1.22313

Cited by 2 publications

(3 citation statements)

References 8 publications

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“…The biological activities of B. glomerulifera have not been explored extensively. As a part of our ongoing research program (Khan et al, 2014;Faruk et al, 2015;Khan et al, 2015) the present study has been undertaken and we, herein, report the antidepressant and anti-diarrheal activities of the leaf extract of B. glomerulifera for the first time.…”

Section: Introductionmentioning

confidence: 85%

Boehmeria glomerulifera Miq. Exhibits in vivo Antidepressant and Antidiarrheal Activities

Shampa¹,

Bari²,

Islam³

et al. 2019

Bangla Pharma J

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Boehmeria glomerulifera Miq., is medicinal herb belongs to the family Urticaceae. It is used for treating various diseases by folk practitioners and rural people. The CNS antidepressant and antidiarrhoeal activities of the crude extract were investigated at 200 and 400 mg/kg bw in Swiss Albino mice model. The crude methanolic extract revealed significant (p < 0.05) antidepressant activity in mice at 400 mg/kg bw. On the other hand, in the castor oil-induced antidiarrheal assay, the extract demonstrated significant (p < 0.05) antidiarrhoeal activity at 400 mg/kg bw. Bangladesh Pharmaceutical Journal 22(2): 181-184, 2019

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Section: Introductionmentioning

confidence: 85%

Boehmeria glomerulifera Miq. Exhibits in vivo Antidepressant and Antidiarrheal Activities

Shampa¹,

Bari²,

Islam³

et al. 2019

Bangla Pharma J

Self Cite

View full text Add to dashboard Cite

show abstract

“…As part our ongoing research program (Khan et al, 2014 the present study has been undertaken and we, herein, report the membrane stabilizing and analgesic activities of the whole plant of B. glomerulifera for the first time.…”

Section: Introductionmentioning

confidence: 99%

“…The ability of the extractives on the stabilization of erythrocytes membrane was evaluated by following the method described by Omale et al (2008) and Khan et al (2014).…”

Section: Membrane Stabilizing Activitymentioning

confidence: 99%

In vitro Membrane Stabilizing and In vivo Analgesic Activities of Boehmeria glomerulifera Miq. in Swiss-Albino Mice Model

et al. 2016

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Boehmeria glomerulifera Miq. is an indigenous plant of Bangladesh. Traditional healers use this plant to treat various diseases. The crude methanol extract of whole plant of B. glomerulifera and its Kupchan fractions were screened for in vitro membrane stabilizing and only the crude extract at doses of 200-and 400-mg/kg body weight were screened for analgesic activity in mice model in order to establish the medicinal values of this plant. The membrane stabilizing activity of the extractives was evaluated by the ability of test materials to inhibit hypotonic solution-and heat-induced haemolysis of human erythrocytes. Moreover, the analgesic activity of methanol extract was evaluated by acetic acid induced writhing method and tail immersion method in mice. In hypotonic solution-and heat-induced conditions, the crude methanol extract showed inhibition of haemolysis by 64.80±0.34% and 21.63±0.76%, respectively as compared to 77.74±0.67% and 40.41±0.69% demonstrated by the standard, acetyl salicylic acid. On the other hand, the analgesic activity was determined for its peripheral and central pharmacological responses using acetic acid-induced writhing test and tail immersion method at doses of 200-and 400-mg/kg body weight. The extract reduced the acetic acid-induced writhings significantly (p < 0.05) in a dose dependent manner with the highest activity observed at 400 mg/kg (46.0%) body weight when compared to that of Diclofenac sodium (64.0%), as the standard drug. A significant increase (p < 0.01) of latency period was also found in tail immersion method. Therefore, the present study established that the methanol extract of B. glomerulifera possesses moderate membrane stabilizing and significant analgesic activities.

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Membrane Stabilizing and Thrombolytic Activities of Sida rhombifolia L.

Cited by 2 publications

References 8 publications

Boehmeria glomerulifera Miq. Exhibits in vivo Antidepressant and Antidiarrheal Activities

Boehmeria glomerulifera Miq. Exhibits in vivo Antidepressant and Antidiarrheal Activities

In vitro Membrane Stabilizing and In vivo Analgesic Activities of Boehmeria glomerulifera Miq. in Swiss-Albino Mice Model

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