Membrane-disruptive homo-polymethacrylate with both hydrophobicity and pH-sensitive protonation for selective cancer therapy

Yu, Rongrong; Geng, Tingting; Wei, Taotian; Wang, Meng; Cao, Yin; Du, Mengting; He, Wei‐Dong; Haleem, Abdul; Hu, Rongfeng; Cao, Yu; Chen, Shengqi

doi:10.1039/d2tb02749f

J. Mater. Chem. B

2023

DOI: 10.1039/d2tb02749f

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Membrane-disruptive homo-polymethacrylate with both hydrophobicity and pH-sensitive protonation for selective cancer therapy

Rongrong Yu

Tingting Geng

Taotian Wei

et al.

Abstract: Membrane-disruptive strategy, such as host defense peptides and their mimetics, is supposed as a revolutionary cancer treatment based on broad-spectrum anticancer activities and ignoring drug resistance. However, the clinical application...

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2024

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Ultra-pH-sensitive nanoparticle of gambogenic acid for tumor targeting therapy via anti-vascular strategy plus immunotherapy

Deng,

Wei,

Zhang

et al. 2024

International Journal of Pharmaceutics

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Ultra-pH-sensitive nanoparticle of gambogenic acid for tumor targeting therapy via anti-vascular strategy plus immunotherapy

Deng,

Wei,

Zhang

et al. 2024

International Journal of Pharmaceutics

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Membrane-disruptive homo-polymethacrylate with both hydrophobicity and pH-sensitive protonation for selective cancer therapy

Abstract: Membrane-disruptive strategy, such as host defense peptides and their mimetics, is supposed as a revolutionary cancer treatment based on broad-spectrum anticancer activities and ignoring drug resistance. However, the clinical application...

Cited by 1 publication

References 30 publications

Ultra-pH-sensitive nanoparticle of gambogenic acid for tumor targeting therapy via anti-vascular strategy plus immunotherapy

Ultra-pH-sensitive nanoparticle of gambogenic acid for tumor targeting therapy via anti-vascular strategy plus immunotherapy

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