Membrane Bound Structures of Peripheral Membrane Binding Proteins TIM3 and TIM1 Produced by Molecular Dynamics Informed Analysis of X-Ray Scattering Experiments

Abstract

growing list of amphitropic proteins that target cell and organelle membranes by sensing lipid packing defects via amphipathic a-helices, suggesting a pathway by which lipid homeostasis regulates mitochondrial function.