Membrane-bound neuraminidase in the developing mouse brain

Differential Expression of Three Sialidase Genes in Rat Development

“…This BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS decline during the period of most intensive protein synthesis is likely due to the dilution of specific enzyme activity following insertion of newly synthesized proteins other than sialidase (29). The previous observations on membrane-bound sialidase in developing mouse brain reported by Segler-Stahl et al (29) were essentially in line with our data. The developmental pattern in liver was similar to that in brain, although the activity level was much lower.…”

Sex and Age Dependence of Rat Kidney Sialidase

“…Similarly to kidney sialyltransferase, the enzyme of bovine serum has been reported to decrease between 2 and 20 days of age when using the same substrate [14], In other mammalian organs, such as human brain [15], rat brain [16] and mouse cerebellum [17], sialidase activity has been found to increase over a period of time after birth until adult levels were reached, whereas in rat liver the enzyme activity is fully active at birth [18]. Other kidney glycosyltransferases (Gal-GlcNAc transferase, Gal-Hyl transfer ase) have been reported to decrease with age as sialyltransferase [19], For what concerns…”