2003
DOI: 10.1074/jbc.m302766200 View full text |Buy / Rent full text
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Abstract: Myelin basic protein (MBP) maintains the compaction of the myelin sheath in the central nervous system by anchoring the cytoplasmic face of the two apposing bilayers and may also play a role in signal transduction. Site-directed spin labeling was done at eight matching sites in each of two recombinant murine MBPs, qC1 (charge ؉19) and qC8 charge (؉13), which, respectively, emulate the native form of the protein (C1) and a posttranslationally modified form (C8) that is increased in multiple sclerosis. When inte… Show more

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