Melodic intonation therapy in post-stroke nonfluent aphasia: a randomized pilot trial

Haro-Martínez, Ana María; Lubrini, Genny; Madero-Jarabo, Rosario; Díez‐Tejedor, Exuperio; Fuentes, Blanca

doi:10.1177/0269215518791004

Cited by 33 publications

(42 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Two were excluded: one for being a topic review ( 16 ) and the other because all the patients received MIT and they were randomized to transcranial direct current stimulation (tDCS) ( 26 ). Therefore, we included a total of 4 trials involving 94 patients in this systematic review ( 27 – 30 ) ( Figure 1 ). Two studies were single, and two were multicenter and one of them used a modification of MIT (MMIT).…”

Section: Resultsmentioning

confidence: 99%

“…Haro et al ( 30 ) was a randomized, crossover, interventional pilot trial. Participants were stroke survivors with post-stroke non-fluent aphasia.…”

Section: Resultsmentioning

confidence: 99%

“…Allocation was correct as well; two studies used consecutively numbered sealed opaque envelopes ( 28 , 29 ) and in the other two studies, the patients were consecutively allocated as long as they were included in the trial ( 30 ) or allocation was performed by a nursing manager who had no prior knowledge of the order of participants ( 27 ). Performance (participant/personnel) bias was considered to be low in one study ( 27 ) and unclear in three studies ( 28 – 30 ). Detection bias was considered low in three studies (blinded measurement of outcomes) ( 27 , 29 , 30 ) and was unclear in one given that the authors acknowledged that blinding could not be maintained because the patients spontaneously informed the researcher about their therapy allocation ( 28 ).…”

Section: Resultsmentioning

confidence: 99%

“…The risk of selection bias was considered to be low; all articles used a computer-generated allocation sequence or a randomization table. Allocation was correct as well; two studies used consecutively numbered sealed opaque envelopes (28,29) and in the other two studies, the patients were consecutively allocated as long as they were included in the trial (30) or allocation was performed by a nursing manager who had no prior knowledge of the order of participants (27). Performance (participant/personnel) bias was considered to be low in one study (27) and unclear in three studies (28)(29)(30).…”

Section: Risk Of Bias In Included Studiesmentioning

confidence: 99%

See 3 more Smart Citations

Melodic Intonation Therapy for Post-stroke Non-fluent Aphasia: Systematic Review and Meta-Analysis

Haro-Martínez

Pérez-Araujo²,

Sanchez-Caro

et al. 2021

Front. Neurol.

Self Cite

View full text Add to dashboard Cite

Introduction: Melodic intonation therapy (MIT) is one of the most studied speech and language therapy (SLT) approaches for patients with non-fluent aphasia, although the methodological quality of the studies has been rated as low in previous reviews. The aim of this study is to update current evidence on the possible efficacy of MIT for the treatment of non-fluent post-stroke aphasia.Methods: A systematic review and meta-analysis. We selected randomized clinical trials (RCT) that included adult patients over 18 years of age with non-fluent post-stroke aphasia, whose intervention was MIT vs. no therapy or other therapy. We excluded non-RCT studies, mixed populations including patients with aphasia of non-stroke etiology, studies with no availability of post-stroke aphasia-specific data, and incomplete studies. Three sections of communicative ability were analyzed as outcomes: functional communication, expressive language (naming and repetition), and comprehension.Results: We identified a total of four eligible RCTs involving 94 patients. Despite the heterogeneity in the psychometric tests employed among the trials, a significant effect of MIT on functional communication (evaluated by the Communication Activity Log) was found (SMD 1.47; 95% CI 0.39–2.56). In addition, a positive effect of MIT on expressive language (repetition) was found (SMD 0.45; 95% CI 0.01–0.90). No significant effects on comprehension measurements were found, despite a lack of significant statistical heterogeneity.Conclusion: This systematic review and meta-analysis shows a significant effect of MIT on improving functional communication and on repetition tasks. Future larger RCT specifically addressing those outcomes should provide the definite evidence on the efficacy of MIT on post-stroke aphasia recovery.Systematic Review Registration:PROSPERO-URL https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020144604.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Haro et al ( 30 ) was a randomized, crossover, interventional pilot trial. Participants were stroke survivors with post-stroke non-fluent aphasia.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Risk Of Bias In Included Studiesmentioning

confidence: 99%

See 2 more Smart Citations

Melodic Intonation Therapy for Post-stroke Non-fluent Aphasia: Systematic Review and Meta-Analysis

Haro-Martínez

Pérez-Araujo²,

Sanchez-Caro

et al. 2021

Front. Neurol.

Self Cite

View full text Add to dashboard Cite

show abstract

“…There is a huge amount of rehabilitation treatment approaches for aphasia in which speech and language therapy (SLT) is the most frequently used therapy, including intensive therapy [ 11 ], melodic intonation therapy [ 12 ], and constraint-induced aphasia therapy (CIAT) [ 13 ]. CIAT, as a noninvasive treatment approach, has attracted great interests in therapists [ 14 , 15 ] since it was first developed by Pulvermüller et al.…”

Section: Introductionmentioning

confidence: 99%

Constraint-induced aphasia therapy for patients with aphasia: A systematic review

Wang

Zheng

et al. 2020

International Journal of Nursing Sciences

View full text Add to dashboard Cite

Objectives This study aimed to systematically evaluate the effects of constraint-induced aphasia therapy (CIAT) for aphasic patients reported by randomized controlled trials. Methods Relevant randomized controlled trials were retrieved from 11 electronic databases. A methodological quality assessment was conducted in accordance with the Cochrane Handbook, and meta-analyses were performed by using RevMan 5.2. A descriptive analysis was conducted when the included trials were not suitable for a meta-analysis. Results A total of 12 trials were included. A statistically significant group difference was shown from the meta-analysis in the results measured by the Western Aphasia Battery (random-effects model, MD = 1.23, 95% CI = 0.31 to 2.14, P < 0.01). However, there were no statistically significant differences shown in the results of the Boston Naming Test (fixed-effects model, MD = −1.79, 95% CI = −11.19 to 7.62, P > 0.05) and Aachen Aphasia Test (fixed-effects model, MD = −1.11, 95% CI = −4.49 to 2.27, P > 0.05). The descriptive analysis showed positive results in language performances of naming, repetition, and comprehension. Conclusion This systematic review indicated that CIAT was efficient for improving language performance with regard to naming, comprehension, repetition, written language, and oral language based on the current evidence. And this review provides some meaningful guides for clinical practice: expand the therapy duration to 2 or 3 h per day, focus on naming, and choose the best assessment tool. It also indicates a need for more rigorous, large-scale, and high-quality trials in the future.

show abstract

Therapie der Aphasie

Grötzbach¹,

Spitzer²

2023

Verschüttete Wörter - Aphasie

View full text Add to dashboard Cite

Melodic intonation therapy in post-stroke nonfluent aphasia: a randomized pilot trial

Abstract: Melodic Intonation Therapy might have a positive effect on the communication skills of stroke survivors with nonfluent aphasia as measured by the CAL questionnaire. A full-scale trial with at least 27 patients per group is necessary to confirm these results.

Cited by 33 publications

References 18 publications

Melodic Intonation Therapy for Post-stroke Non-fluent Aphasia: Systematic Review and Meta-Analysis

Melodic Intonation Therapy for Post-stroke Non-fluent Aphasia: Systematic Review and Meta-Analysis

Constraint-induced aphasia therapy for patients with aphasia: A systematic review

Therapie der Aphasie

Contact Info

Product

Resources

About