Melatonin use in menopausal metabolic syndrome treatment.

Abstract

Women in menopause have increased risk of such diseases, which is caused by nonreversible hormonal changes in the organism. At the current moment, it is well-known that in menopause conditions the decrease not only of the reproductive hormones level, but also of the epiphyseal melatonin hormone level, is observed. It was found out that parasecretion of the indoleamine is observed in the menopausal metabolic syndrome conditions. The scientific publications search was held in Russian and international data bases in the Russian and English languages. The article focuses on the experience of melatonin use in the complex therapy of metabolic syndrome, including women in post menopause. The results of researches, in which the melatonin influence on separate metabolic syndrome symptoms is studied, are examined in the article. Moreover, the article observes several scientific works, in which melatonin was used in metabolic syndrome treatment as a means of monotherapy. The analysis of the data allows us to conclude, that melatonin may be effectively used in the complex metabolic (including menopause) syndrome treatment.