Melatonin protects zebrafish pancreatic development and physiological rhythms from sodium propionate‐induced disturbances via the hypothalamic–pituitary–thyroid axis
Yixin Xu,
Shuhui Zhang,
Yehua Bao
et al.
Abstract:BACKGROUNDThe widespread use of sodium propionate as a preservative in food may affect public health. We aimed to assess the effects of sodium propionate on circadian rhythms and pancreatic development in zebrafish and the possible underlying mechanisms.RESULTSIn this experiment, we analyzed the relationship between circadian rhythms and pancreatic development and then revealed the role of the thyroid endocrine system in zebrafish. The results showed that sodium propionate interfered with the rhythmic behavior… Show more
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