Melatonin Induces Disease Resistance to <i>Botrytis cinerea</i> in Tomato Fruit by Activating Jasmonic Acid Signaling Pathway

Liu, Chunxue; Chen, Lingling; Zhao, Ruirui; Li, Rui; Zhang, Shujuan; Yu, Wenqing; Sheng, Jiping; Shen, Lin

doi:10.1021/acs.jafc.9b00058

Cited by 165 publications

(100 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, results from some investigations support the hypothesis that melatonin increases phagocytic activity and decreases oxidative stress during candidiasis [60][61][62]. In a plant-fungi interaction model, melatonin played a promotional role in the resistance of tomato fruit to Botrytis cinerea via the regulation of H 2 O 2 generation and the jasmonic acid signaling mechanism [63]. Melatonin can increase fungicide susceptibility, enhance vulnerability of Phytophthora infestans to different environmental stress, decrease the dosage level, and promote the efficiency of fungicide treatment against potato late blight [64].…”

Section: Antifungal Effect Of Melatoninmentioning

confidence: 67%

Melatonin and Its Protective Role against Biotic Stress Impacts on Plants

Almoneafy²,

et al. 2019

View full text Add to dashboard Cite

A.A.); shaoyingai@21cn.com (S.A.); Tel.: +86-186-8050-4072 (M.M.-F.); +967-777766831 (A.A); +86-020-3288-5970 (S.A.) † These authors contributed equally to this work.Abstract: Biotic stress causes immense damage to agricultural products worldwide and raises the risk of hunger in many areas. Plants themselves tolerate biotic stresses via several pathways, including pathogen-associated molecular patterns (PAMPs), which trigger immunity and plant resistance (R) proteins. On the other hand, humans use several non-ecofriendly methods to control biotic stresses, such as chemical applications. Compared with chemical control, melatonin is an ecofriendly compound that is an economical alternative strategy which can be used to protect animals and plants from attacks via pathogens. In plants, the bactericidal capacity of melatonin was verified against Mycobacterium tuberculosis, as well as multidrug-resistant Gram-negative and -positive bacteria under in vitro conditions. Regarding plant-bacteria interaction, melatonin has presented effective antibacterial activities against phytobacterial pathogens. In plant-fungi interaction models, melatonin was found to play a key role in plant resistance to Botrytis cinerea, to increase fungicide susceptibility, and to reduce the stress tolerance of Phytophthora infestans. In plant-virus interaction models, melatonin not only efficiently eradicated apple stem grooving virus (ASGV) from apple shoots in vitro (making it useful for the production of virus-free plants) but also reduced tobacco mosaic virus (TMV) viral RNA and virus concentration in infected Nicotiana glutinosa and Solanum lycopersicum seedlings. Indeed, melatonin has unique advantages in plant growth regulation and increasing plant resistance effectiveness against different forms of biotic and abiotic stress. Although considerable work has been done regarding the role of melatonin in plant tolerance to abiotic stresses, its role in biotic stress remains unclear and requires clarification. In our review, we summarize the work that has been accomplished so far; highlight melatonin's function in plant tolerance to pathogens such as bacteria, viruses, and fungi; and determine the direction required for future studies on this topic.

show abstract

Section: Antifungal Effect Of Melatoninmentioning

confidence: 67%

Melatonin and Its Protective Role against Biotic Stress Impacts on Plants

Almoneafy²,

et al. 2019

View full text Add to dashboard Cite

show abstract

“…A large number of genes, involved in MAPK signaling, nucleotide metabolism, and ethylene biosynthesis, are transcriptionally reprogrammed by melatonin treatment, suggesting the possible role of melatonin as a signal molecule (Xu et al, 2017). Furthermore, exogenous melatonin treatment could promote methyl jasmonate (MeJA) accumulation and enhance the expression of proteinase inhibitor II in tomato fruits, which results in the up-regulation of JA defense signaling that is a crucial pathway in pathogen resistance (Liu et al, 2019). Other studies showed that melatonin is involved in abscisic acid and cytokinin metabolic signaling pathways regulating heat stress response in perennial ryegrass (Zhang et al, 2017a), and participates in adventitious root development by regulating auxin and nitric oxide signaling in tomato plants (Wen et al, 2016).…”

Section: Mechanisms Of Exogenous Melatonin Functions In Post-harvest mentioning

confidence: 99%

Melatonin Is a Potential Target for Improving Post-Harvest Preservation of Fruits and Vegetables

Chen

Kang

2019

Front. Plant Sci.

View full text Add to dashboard Cite

Melatonin is a ubiquitous molecule distributed in nature and not only plays an important role in animals and humans but also has extensive functions in plants, such as delaying senescence, exerting antioxidant effects, regulating growth and development, and facilitating plant adaption to stress conditions. Endogenous melatonin is widespread in fruits and vegetables and plays prominent roles in the ripening and post-harvest process of fruits and vegetables. Exogenous application of melatonin removes excess reactive oxygen species from post-harvest fruits and vegetables by increasing antioxidant enzymes, non-enzymatic antioxidants, and enzymes related to oxidized protein repair. Moreover, exogenous application of melatonin can increase endogenous melatonin to augment its effects on various physiological processes. Many previous reports have demonstrated that application of exogenous melatonin improves the post-harvest preservation of fruits and vegetables. Although overproduction of melatonin in plants via transgenic approaches could be a potential means for improving the post-harvest preservation of fruits and vegetables, efforts to increase endogenous melatonin in plants are limited. In this review, we summarize the recent progress revealing the role and action mechanisms of melatonin in post-harvest fruits and vegetables and provide future directions for the utilization of melatonin to improve the post-harvest preservation of fruits and vegetables.

show abstract

Section: Introductionmentioning

confidence: 99%

“…As the most commonly known members of phytohormones, Jasmonic acid (JA) signaling pathways were reported to have an active effect on inhibiting gray mold ( Liu et al., 2019 ). It was generally believed that activating of JA signaling pathway can induce resistance against necrotrophs ( Liu et al., 2019 ) and endogenous contents of JAs was rapidly up-regulated and then triggered the formation of COI1-JA-JAZ ternary complex to induce degradation of the Jasmonate-ZIM domain (JAZ) proteins ( Zhang et al., 2019 ). The basic helix-loop-helix (bHLH) transcription factor MYC2 acted as a key regulator in the JA signaling pathway ( Boter et al., 2004 ; Lorenzo et al., 2004 ; Dombrecht et al., 2007 ) and transcriptional activity of MYC2 was repressed by JAZ ( Chini et al., 2007 ; Thines et al., 2007 ; Pauwels et al., 2010 ).…”

Section: Introductionmentioning

confidence: 99%

Redox Status, JA and ET Signaling Pathway Regulating Responses to Botrytis cinerea Infection Between the Resistant Cucumber Genotype and Its Susceptible Mutant

et al. 2020

View full text Add to dashboard Cite

Botrytis cinerea is an important necrotrophic fungal pathogen with a broad host range and the ability to causing great economic losses in cucumber. However, the resistance mechanism against this pathogen in cucumber was not well understood. In this study, the microscopic observation of the spore growth, redox status measurements and transcriptome analysis were carried out after Botrytis cinerea infection in the resistant genotype No.26 and its susceptible mutant 26M. Results revealed shorter hypha, lower rate of spore germination, less acceleration of H 2 O 2 , O 2-, and lower total glutathione content (GSH+GSSG) in No.26 than that in 26M, which were identified by the staining result of DAB and NBT. Transcriptome data showed that after pathogen infection, a total of 3901 and 789 different expression genes (DEGs) were identified in No.26 and 26M respectively. These DEGs were highly enriched in redox regulation pathway, hormone signaling pathway and plant-pathogen interaction pathway. The glutathione S-transferase genes, putative peroxidase gene, and NADPH oxidase were up-regulated in No.26 whereas these genes changed little in 26M after Botrytis cinerea infection. Jasmonic acid and ethylene biosynthesis and signaling pathways were distinctively activated in No.26 comparing with 26M upon infection. Much more plant defense related genes including mitogen-activated protein kinases, calmodulin, calmodulin-like protein, calciumdependent protein kinase, and WRKY transcription factor were induced in No.26 than 26M after pathogen infection. Finally, a model was established which elucidated the resistance difference between resistant cucumber genotype and susceptible mutant after B. cinerea infection.

show abstract

Melatonin Induces Disease Resistance to Botrytis cinerea in Tomato Fruit by Activating Jasmonic Acid Signaling Pathway

Cited by 165 publications

References 57 publications

Melatonin and Its Protective Role against Biotic Stress Impacts on Plants

Melatonin and Its Protective Role against Biotic Stress Impacts on Plants

Melatonin Is a Potential Target for Improving Post-Harvest Preservation of Fruits and Vegetables

Redox Status, JA and ET Signaling Pathway Regulating Responses to Botrytis cinerea Infection Between the Resistant Cucumber Genotype and Its Susceptible Mutant

Contact Info

Product

Resources

About