2008
DOI: 10.2478/v10039-008-0032-x
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Melatonin in relation to the "strong" and "weak" versions of the free radical theory of aging

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Cited by 45 publications
(41 citation statements)
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References 80 publications
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“…This is consistent with the opinion that melatonin influences the activity and expression of the antioxidative enzymes, i.e. glutathione peroxidase, SOD, and CAT (13,(23)(24)(25), as well as antioxidant vitamins (26).…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…This is consistent with the opinion that melatonin influences the activity and expression of the antioxidative enzymes, i.e. glutathione peroxidase, SOD, and CAT (13,(23)(24)(25), as well as antioxidant vitamins (26).…”
Section: Discussionsupporting
confidence: 92%
“…It is known that melatonin can act as an antioxidant (12)(13)(14)(15), the functions of which are to reduce the level of reactive oxygen species (ROS) and to stimulate the activity of antioxidant enzymes. Knowledge regarding the influence of melatonin implants on the antioxidants of farmed canines is very limited.…”
Section: Introductionmentioning
confidence: 99%
“…It has been suggested that the age-related changes in sleep are partly due to a decrease in circadian amplitude (47). It has also long been known that endogenous melatonin production declines with increasing age (48). This may offer an explanation as to why the effects of Horlicks are more effective after serial administration in older adults but not in younger adults.…”
Section: Sleep-promoting Foods and Sleep Quality: Experimental Findingsmentioning
confidence: 90%
“…Aging is associated with a decline in nighttime sleep quality (47) as well as with changes in the circadian regulation of the sleep-wake cycle (48). It has been suggested that the age-related changes in sleep are partly due to a decrease in circadian amplitude (47).…”
Section: Sleep-promoting Foods and Sleep Quality: Experimental Findingsmentioning
confidence: 99%
“…Bazı çalışmalarda ise melatoninin antioksidan ve serbest radikal süpürücü etkisinin reseptör aracılı olmadığı ve bu etkilerin fizyolojik konsantrasyonların üzerinde oluştuğu bildirilmektedir (28)(29)(30) Wichmann ve arkadaşları farelerde yumuşak doku travması ve hemorajik şok sonucu immun fonksiyonlardaki baskılan-manın melatonin ile geri çevrildiği, ayrıca kronik melatonin tedavisinin insanda lökosit naturel killer aktivitesini artırdığı-nı bildirmişlerdir (45).…”
Section: Melatonin Antioksidan Etkileriunclassified