Melatonin facilitates oocyte growth in goats and mice through increased nutrient reserves and enhanced mitochondrial function
Changjiu He,
Hao Wu,
Ruiyan Liu
et al.
Abstract:Oogenesis involves two phases: initial volumetric growth driven by nutrient accumulation and subsequent nuclear maturation. While melatonin (MLT) has been employed as a supplement to enhance the quality of fully grown oocytes during nuclear maturation phase, its impact on oocyte growth remains poorly studied. Here, we provide in vivo evidence demonstrating that follicle‐stimulating hormone increases MLT content in ovary. Administration of MLT improves oocyte growth and quality in mice and goats by enhancing nu… Show more
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