Melatonin and roentgen irradiation of the testis

Antioxidant Systems and Oxidative Stress in the Testes

“…This evolutionarily conserved compound has been shown to reduce oxidative stress in the testes induced by ethanol,167 indomethacin,168 X-irradiation,169 streptozotocin-induced diabetes,86 and cisplatin 136. In vitro studies have also shown that melatonin and its immediate precursor N-acetyl-serotonin could inhibit ascorbate-Fe (II) induced lipid peroxidation in rat testicular microsomes and mitochondria 170,171…”

Antioxidant Systems and Oxidative Stress in the Testes

“…166 One of the most effective antioxidants for the protection of testicular function is melatonin. This evolutionarily conserved compound has been shown to reduce oxidative stress in the testes induced by ethanol, 167 indomethacin, 168 X-irradiation, 169 streptozotocin-induced diabetes, 86 and cisplatin. 136 In vitro studies have also shown that melatonin and its immediate precursor N-acetyl-serotonin could inhibit ascorbate-Fe (II) induced lipid peroxidation in rat testicular microsomes and mitochondria.…”

Melatonin and roentgen irradiation‐induced acute radiation enteritis in Albino rats: An animal model

“…All rats were given ad libitum access to Taklad rodent chow diet and water from sanitized bottle fitted with stopper and sipper tubes. These conditions were adopted following other groups (Hussein et al, , 2006a.…”