Melanotic neuroectodermal tumor of infancy

Lee, Chong Heon; Hong, Seong Wook; Lim, Chae Young

doi:10.3346/jkms.1986.1.1.63

Cited by 7 publications

(7 citation statements)

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“…Mummery and Pitts in 1926 reported a pigmented maxillary tumor of a 5-month-old female infant under the name of melanotic epithelial odontoma, an ascertaining its origin to be from odontogenic apparatus from the viewpoint that it occurs predominately in maxilla and have used the term “melanotic or pigmented ameloblastoma”, suggesting that the tumor might arise from some proliferative, and aberrant odontogenic epithelium. [ 17 ]…”

Section: Discussionmentioning

confidence: 99%

“…Dehner et al, describe various stages of melanocytes and neuroblast like cells, suggesting neuroectodermal origin. [ 17 ] Hence, the term “melanotic neuroectodermal tumor” was coined.…”

Section: Discussionmentioning

confidence: 99%

“…Although high levels of VMA are common findings in the individuals with neural cell tumors such as pheochromocytoma, ganglioneuroblastoma, neuroblastoma, and retinoblastoma, indicating tumor originating from neural crest. [ 17 ]…”

Section: Discussionmentioning

confidence: 99%

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Melanotic neuroectodermal tumor of infancy: Report of a case associated with high urinary excretion of Vanilmandelic acid

Sah

Kale

et al. 2011

Contemp Clin Dent

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Melanotic neuroectodermal tumor of infancy is a rare congenital neoplasm involving the head and neck region in young patients. A case of melanotic neuroectodermal tumor of infancy is presented. This tumor occurred in right maxillary alveolar ridge in a 4-month-old infant. The present case showed an increased urinary level of vanilmandelic acid, confirming that the tumor is originated from neural crest. Clinical assessment, histologic diagnosis, and laboratory findings supported the diagnosis.

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Section: Discussionmentioning

confidence: 99%

“…Dehner et al, describe various stages of melanocytes and neuroblast like cells, suggesting neuroectodermal origin. [ 17 ] Hence, the term “melanotic neuroectodermal tumor” was coined.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Melanotic neuroectodermal tumor of infancy: Report of a case associated with high urinary excretion of Vanilmandelic acid

Sah

Kale

et al. 2011

Contemp Clin Dent

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“…On the other hand, high levels of VMA are common findings in the individuals with neural cell tumors such as neuroblastoma, retinoblastoma, pheochromocytoma, and ganglioneuroblastoma, indicating neural crest origin of the tumor. 15 The surgical excision is the classical treatment in large lesions. CEN never recurs even if the removal is incomplete.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis and management of congenital epulis of new-born: a rare case report and literature review

Ottoman

2015

Int J Sci Rep

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The congenital epulis of new-born is a rare disease of idiopathic etiology and lineage. The literature recorded spontaneous regression of some cases. This finding rendered skeptical questions about its neoplastic nature and posed some speculations about hormonal influences, towards the end of pregnancy, on the growth of the lesion. No malignant potential has been ever reported. Surgery is indicated if the lesion grossly interferes with breast feeding. This paper reports an established diagnosis of congenital epulis of new-born, which was excised surgically with no evidence of recurrence hitherto. Keywords: Congenital epulis, Neonatal lesions, Mucosal swellings, Pediatric oncology

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“…Krompecher made the first description of this tumor in 1918 as a congenital melanocarcinoma. [ 1 ] In 1966, Borello and Gorlin reported a case characterized by a high urinary excretion of vanillylmandelic acid (VMA), classically found in a pheochromocytoma as well as in other neuroblastic tumors, suggesting a neuroectodermal origin of the lesion. [ 1 ]…”

Section: Introductionmentioning

confidence: 99%

Melanotic neuroectodermal tumor of infancy: A rare case report

et al. 2013

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Melanotic neuroectodermal tumor of infancy (MNTI) is a relatively uncommon osteolytic-pigmented neoplasm that primarily affects the jaws of infants. The early onset and its rapid disfiguring spread necessitate early diagnosis. A 4-month-old male child reported with the complaint of swelling in the right back tooth region of the upper jaw, which rapidly increased in size causing disfigurement of the face. Radiographic examination showed a diffuse osteolytic radiolucent lesion in the right maxilla and displacement and dysmorphic changes in the developing primary tooth buds. Wide surgical excision was performed under general anesthesia. Histopathological report revealed characteristic large pigmented epitheloid cells (melanocyte like cells). The biphasic tumor cell population arranged in a background of fibrous connective tissue stroma is suggestive of MNTI involving the cancellous bone. Early diagnosis and management of such aggressive tumors precludes significant morbidity of the patient.

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Melanotic neuroectodermal tumor of infancy

Cited by 7 publications

References 0 publications

Melanotic neuroectodermal tumor of infancy: Report of a case associated with high urinary excretion of Vanilmandelic acid

Melanotic neuroectodermal tumor of infancy: Report of a case associated with high urinary excretion of Vanilmandelic acid

Diagnosis and management of congenital epulis of new-born: a rare case report and literature review

Melanotic neuroectodermal tumor of infancy: A rare case report

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