Melanoma in situ of the penis

Demitsu, Toshio; Nagato, Hajime; Nishimaki, Keiko; Okada, Osamu; Kubôta, Takashi; Yoneda, Kozo; Manabe, Motomu

doi:10.1016/s0190-9622(00)90120-8

Cited by 41 publications

(31 citation statements)

References 9 publications

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“…Most cases of malignant melanoma of the penis occur in patients in their sixth and seventh decades18. So, when choosing a therapeutic option for a kissing nevus of the penis, the focus should be on esthetic and functional outcome.…”

Section: Discussionmentioning

confidence: 99%

Kissing Nevus of the Penis

Yun

Lee

et al. 2011

Ann Dermatol

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Kissing or divided nevi are similar in shape to congenital melanocytic nevi located on an adjacent part of the body that are separated during embryogenesis. Kissing nevi of the upper and lower eyelids have been reported infrequently since the first report in 1908. Kissing nevi of the penis are very rare, with only 12 cases being reported until now, and this is the first case report in the Korean dermatological literature. A previously healthy 27-year-old man presented with asymptomatic black colored patches, which were detected 10 years ago, on the glans penis and the prepuce with growth in size. We report here a case of kissing nevus of the penis, which showed an obvious mirror-image symmetry relative to the coronal sulcus.

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Section: Discussionmentioning

confidence: 99%

Kissing Nevus of the Penis

Yun

Lee

et al. 2011

Ann Dermatol

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“…SSM is the most common melanoma that can occur at any site and at any age [48]. About 75% of SSMs occur de novo.…”

Section: Classification and Histopathologymentioning

confidence: 99%

From Melanocyte to Metastatic Malignant Melanoma

Bandarchi

Navab

et al. 2010

Dermatology Research and Practice

115

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Malignant melanoma is one of the most aggressive malignancies in human and is responsible for almost 60% of lethal skin tumors. Its incidence has been increasing in white population in the past two decades. There is a complex interaction of environmental (exogenous) and endogenous, including genetic, risk factors in developing malignant melanoma. 8–12% of familial melanomas occur in a familial setting related to mutation of the CDKN2A gene that encodes p16. The aim of this is to briefly review the microanatomy and physiology of the melanocytes, epidemiology, risk factors, clinical presentation, historical classification and histopathology and, more in details, the most recent discoveries in biology and genetics of malignant melanoma. At the end, the final version of 2009 AJCC malignant melanoma staging and classification is presented.

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“…Penile melanoma is exceptionally rare, accounting for less than 2% of all primary malignant lesions of the penis. Most arise in the sixth or seventh decade of life [4]. Furthermore, of the eight reported cases of divided nevi of the penis, only one underwent malignant transformation [2].…”

Section: Discussionmentioning

confidence: 99%