Melanoma and Pregnancy

El-Minawi, Mahmoud F.; Hori, Jose M.; Donegan, William L.

doi:10.1002/j.1879-3479.1973.tb00863.x

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…Arguments in favor of our view are: (1) the patient's history, which revealed the presence of the scalp lesion which was removed 2 Vi years prior to the extirpation of the ovarian teratomas and (2) of bilateral metastatic malignant melanoma in the corpora lutea of binovular twin pregnancy, 12 and its relation to pregnancy was discussed in detail. 13 Only two of the 11 reported cases of the so-called primary malignant melanoma of the ovary were bilateral. 27,29 Bilaterality, per se, does not necessarily indicate a metastatic origin, but because of the tendency of these tumors to spread by the vascular system, it is always a strong possibility.…”

Section: Commentmentioning

confidence: 99%

Malignant Melanoma in Bilateral Dermoid Cysts of the Ovary

El-Minawi

Hori

1973

Intl J Gynecology & Obste

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Section: Commentmentioning

confidence: 99%

Malignant Melanoma in Bilateral Dermoid Cysts of the Ovary

El-Minawi

Hori

1973

Intl J Gynecology & Obste

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Better prognosis of many cancers in female: A phenomenon not explained by study of steroid receptors

Lee

1984

J. Surg. Oncol.

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Experimental evidence indicates that specific sex hormonal imbalance, deficiency, and excess may be causes of tumors or at least contribute in some way to their development. Clinical observations show that the prognoses of patients with various malignancies differ among males and females, and some cancers can be alleviated and partially controlled by altering the accustomed hormonal environment. Although beneficial effects usually are only temporary, there is no doubt that some cancers are hormone-dependent to a degree. A significant number of prostatic carcinoma in males and breast carcinoma in both sexes have been treated with various additive or ablative endocrine manipulations. The detection and quantitation of specific steroid binding proteins in hormone-sensitive tumors have enhanced our understanding of the mechanism of endocrinal therapy. Excluding carcinoma of the breast and of the sex organs (ovary and uterus in females, testis and prostate in males), many other solid tumors have been tested for the presence of estrogen and other steroid receptors. A fair number of solid cancers contains estrogen and progesterone receptors (ER, PR), even those from male patients. Thus, the better prognosis of females with sarcoma, melanoma, liver, colorectal and other cancers cannot simply be explained by the presence or absence of estrogen or progesterone receptors. This review attempts to summarize clinical reports of this interesting phenomenon, including therapeutic results with estrogenic, antiestrogenic, and other hormonal approaches.

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Melanoma and Pregnancy

Cited by 2 publications

References 15 publications

Malignant Melanoma in Bilateral Dermoid Cysts of the Ovary

Malignant Melanoma in Bilateral Dermoid Cysts of the Ovary

Better prognosis of many cancers in female: A phenomenon not explained by study of steroid receptors

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