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Cited by 2 publications
(3 citation statements)
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“…30 The HM19 cell line may provide a missing research tool also for studying the biology of this disease manifestation. 17,19,30,31 The intracardiac injection of cells results in hematogenous spread throughout the animals, in our case with a very good take rate (90%). However, this approach also has its clear limitations as 500,000 tumor cells were injected over a very short period into the systemic circulation, a situation that can lead to intravascular cancer cell aggregates, and misguided injections may result in perfusion to the pulmonary circulation or thorax.…”
Section: Discussionsupporting
confidence: 49%
See 1 more Smart Citation
“…30 The HM19 cell line may provide a missing research tool also for studying the biology of this disease manifestation. 17,19,30,31 The intracardiac injection of cells results in hematogenous spread throughout the animals, in our case with a very good take rate (90%). However, this approach also has its clear limitations as 500,000 tumor cells were injected over a very short period into the systemic circulation, a situation that can lead to intravascular cancer cell aggregates, and misguided injections may result in perfusion to the pulmonary circulation or thorax.…”
Section: Discussionsupporting
confidence: 49%
“…However, it is known that clinical leptomeningeal MM metastases are associated with rapid disease progression with a mean survival of only 8–10 weeks after being diagnosed 30 . The HM19 cell line may provide a missing research tool also for studying the biology of this disease manifestation 17,19,30,31 …”
Section: Discussionmentioning
confidence: 99%
“…The World Health Organization (WHO) classification divides the melanocytic lesions of the central nervous system into three types: diffuse melanosis, meningeal melanocytoma (benign course), and melanoma [ 210 ]. Considering the latter, two forms of PIMM should be highlighted: solid tumors and diffuse meningeal melanomatosis [ 211 ].…”
Section: Unusual or Unknown Primary Site Melanomasmentioning
confidence: 99%