2013
DOI: 10.1111/jdv.12291
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Melanocytic nevi with special features: clinical‐dermoscopic and reflectance confocal microscopic‐findings

Abstract: Histopathology is considered the 'gold' standard for the diagnosis and classification of melanocytic nevi, but the widespread use of in vivo diagnostic technologies such as dermoscopy and reflectance confocal microscopy (RCM), has enriched profoundly the knowledge regarding the morphological variability in nevi. This is because most morphological observations made via these in vivo tools are closely correlated with features seen in histopathology. Dermoscopy has allowed for a more detailed classification of ne… Show more

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Cited by 40 publications
(40 citation statements)
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“…Several studies showed diminished expression of interleukin-2 receptors in the lymphocytic infiltrate, suggesting that the involved mechanisms differ from those of allergic contact dermatitis [2,12]. Occasional eosinophils in the superficial dermis suggest a possible hypersensitivity process.…”
Section: Discussionmentioning
confidence: 99%
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“…Several studies showed diminished expression of interleukin-2 receptors in the lymphocytic infiltrate, suggesting that the involved mechanisms differ from those of allergic contact dermatitis [2,12]. Occasional eosinophils in the superficial dermis suggest a possible hypersensitivity process.…”
Section: Discussionmentioning
confidence: 99%
“…Meyerson's phenomenon can be confined to one, some or all nevi in a given patient. It was also described in association with some nonmelanocytic lesions, including seborrheic keratosis, histiocytofibroma, basal cell carcinoma, squamous cell carcinoma, sebaceous nevus, vascular malformations, insect bites, keloids and molluscum contagiosum [12,13,14,15]. Meyerson's nevi are more common in adult males, typically arising on the trunk and proximal extremities [1].…”
Section: Introductionmentioning
confidence: 99%
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“…Sclerosing nevi with pseudomelanomatous features or nevi with regression‐like fibrosis present a recently classified entity simulating regressing melanoma induced by minor trauma on pre‐existing nevi . These nevi are typically found on the convex area of the back of young to middle‐aged men . A typical trizonal pattern can be observed in histopathology: (i) atypical junctional proliferation and pagetoid spreading; (ii) atypical melanocytic nests within dermal sclerosis; and (iii) residual nevus tissue surrounding and within the cicatricial tissue.…”
Section: Nevi With Special Featuresmentioning
confidence: 99%
“…Reflectance confocal microscopy (RCM) of HN has been previously described in 2 studies and some atypical features, also seen in atypical melanocytic lesions and malignant melanoma, were observed in most patients evaluated. These features included pagetoid cells, non-edged papilla, junctional thickening, nucleated cells in the dermal papillae, and plump bright cells 6, 7. These atypical findings might be due to local inflammation 7 …”
Section: Introductionmentioning
confidence: 99%