The air salinity in coastal area may contribute significant effects to the growth of plants. Physiological aspects of the plant growth of plants are important information to give optimal treatments during cultivation process. One potential plant cultivated on coastal area is corns. This study aimed to study the physiological response of corn's growth to certain air salinity condition during cultivation on coastal area, and to determine their salinity tolerance index. The research was conducted in a screen house at the experimental farm of the Faculty of Agriculture, Jenderal Soedirman University, from July to November 2021. The study was conducted using method of Randomized completely Block design factorial with two factors. The first factor is the corn varieties (Bonanza -9 F1 and Bisi-18), and the second factor is air salinity (0 mS, 6 mS, 12 mS, and 18 mS). The data were analyzed by using the Anova, and continue to 5% Duncan's Multiple Range Test (DMRT), when the result is significantly different. The observed variables were plant height, number of leaves, leaf area, root length, fresh root weight, root dry weight, stem fresh weight, dry stem weight, fresh leaf weight, dry leaf weight, and chlorophyll a and b, proline content, stomata density, widht stomata opening, fresh weight of corn cob, dry weight of corn cob, seed fresh weight, dry seed weight, and number of seeds. The results of the research showed that the tolerance index of the Bisi-18 corn was higher than Bonanza 9-F1 corn, which showing better physiology aspects of chlorophyll content and proline content. The 6 mS air salinity treatment reduced chlorophyll content at the end of vegetative and generative, leaf area, fresh and dry weight of seeds, and the number of corn seeds. The 18 mS air salinity treatment showed the highest proline content and decreased at 12 mS and 6 mS treatments. The interaction of treatments on proline content, stem fresh weight, and chlorophyll content showed that Bonanza 9-F1 corn plants with 18 mS air salinity treatment showed the highest yields. The tolerance level of the Bisi-18 corn showed that the plant was still tolerant at 18 mS salinity. In comparison, the Bonanza 9-F1 corn showed intolerant results at 6 mS air salinity.