Meiosis in the foetal mouse ovary

Speed, R. M.

doi:10.1007/bf00330366

Cited by 147 publications

(31 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is in contrast to the regular presence of a chromosome bouquet at zygotene and early pachytene in most other organisms (2,17) including the female mouse (35). If bouquet formation is a regular feature of chromosome pairing in mouse spermatocytes, it appears in most nuclei to be resolved before the late zygotene-eady pachytene stages.…”

Section: The Synaptonemal Complex Complementmentioning

confidence: 82%

Crossing over in the male mouse as analysed by recombination nodules and bars

Glamann

1986

Carlsberg Res. Commun.

View full text Add to dashboard Cite

The present study of 26 serially sectioned mouse spermatocyte nuclei has permitted the following observations and conclusions: l) The pachytene stage can be subdivided into an early, a mid, and a late substage. 2) A morphological change of the early spheric recombination nodule to an elongated bar is observed.3) The number of recombination structures per nucleusdecreases from a mean of 31 nodules and 2 bars at early pachytene to a mean of 8 nodules and 6 bars at mid pachytene. The number of nodules and bars remains virtually constant at late pachytene and early diplotene. 4) The number of bivalents with one and two nodules is higher than would be expected if the nodules were distributed at random. 5) Along the bivalents the frequency of nodules and bars exhibits a characteristic pattern of troughs and peaks. 6) The presence of a nodule/bar distally in the synaptonemal complex segment combining the X and the Y chromosomes strongly indicates the existence of an obligatory crossover between the terminal parts of the long arm of the X and Y chromosomes.

show abstract

Section: The Synaptonemal Complex Complementmentioning

confidence: 82%

Crossing over in the male mouse as analysed by recombination nodules and bars

Glamann

1986

Carlsberg Res. Commun.

View full text Add to dashboard Cite

show abstract

“…The progression of pairing during this stage is not synchronous. This tact has been described in different species by other authors (Moses, 1977;Pathak & Hsu, 1979;Speed, 1982;Dietrich & De Boer, 1983;Bojko, 1983;Vidal et al, 1984;Freixa et al, 1985;Wallace & Hultdn, 1985). During this stage the SCs become shorter and thicker.…”

Section: Zygotenementioning

confidence: 94%

“…In recent years, several papers have been published on synaptonemal complexes in different mammalian species (Bojko, 1983;Dietrich, 1983;Speed, 1982;1983;1985;Freixa et al 1983;1985;Guitart et al 1985;Wallace, 1985;Tease, 1986). However, no data have been published on the formation of synaptonemal complexes in female rats.…”

Section: Introductionmentioning

confidence: 99%

Sequential study of the synaptonemal complex in rat (Rattus norvegicus) oocytes by light and electron microscopy

et al. 1988

View full text Add to dashboard Cite

The progression of first meiotic prophase and synaptonemal complex (SC) formation in female rats, Rattus norvegicus S.D., is described through the analysis of the different stages of the first meiotic prophase, and confirms the high synchrony of the process in this species. Leptotene is a stage of very short duration and since pairing of the homologues begins very early, only a leptotene-zygotene stage can be distinguished. The progression of pairing during zygotene is asynchronous. The morphology of the SCs is similar to that described in other species. During diplotene and before disintegration of the lateral elements, desynapsis takes place. In some oocytes a double or even multiple nature of lateral elements was seen. Associations between SCs and nucleoli or nucleolar filaments are frequent. The presence of fragmented SCs can be interpreted as a technical artifact.

show abstract

“…In addition, nuclei were imaged from oocytes from 16-to 18-day old fetuses taken from pregnant females. Surface spreads from both spermatocytes and oocytes were prepared using the method of Speed (25), as modified by Antoine Peters (personal communication). Antibody incubation and detection was a modification of that of Moens et al (26) as described by Ashley et al (27).…”

Section: Methodsmentioning

confidence: 99%

Evidence for a role for DNA polymerase β in mammalian meiosis

Plug

Clairmont

Sapi

et al. 1997

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

DNA polymerase ␤ (pol ␤) is an enzyme possessing both polymerase and deoxyribose phophatase activities. Although pol ␤ is not believed to participate in the replication of genomic DNA, several studies have indicated a role for pol ␤ in DNA repair. The high level of expression of pol ␤ in mouse and rat testes raises the possibility that pol ␤ participates in mammalian meiosis. Using antibody localization, we detect foci that stain with pol ␤ antisera at discrete sites along homologous chromosomes as they synapse and progress through prophase of meiosis I. These data suggest that pol ␤ participates in meiotic events associated with synapsis and recombination.

show abstract

Meiosis in the foetal mouse ovary

Cited by 147 publications

References 22 publications

Crossing over in the male mouse as analysed by recombination nodules and bars

Crossing over in the male mouse as analysed by recombination nodules and bars

Sequential study of the synaptonemal complex in rat (Rattus norvegicus) oocytes by light and electron microscopy

Evidence for a role for DNA polymerase β in mammalian meiosis

Contact Info

Product

Resources

About