Megastigmane O-glucopyranosides from Litsea glutinosa

Chemical Constituents from the Aerial Parts of Agastache rugosa and Their Inhibitory Activities on Prostaglandin E2 Production in Lipopolysaccharide-Treated RAW 264.7 Macrophages

“…Additionally, 26 known compounds were assigned as acacetin-7- O -(2″- O -acetyl-6″- O -malonyl)-β- d -glucopyranoside ( 2 ), acacetin-7 -O -(6″- O -malonyl) - β- d -glucopyranoside ( 3 ), acacetin-7- O -(3″- O -acetyl)-β- d -glucopyranoside ( 4 ), isoagastachoside ( 5 ), diosmetin-7- O -β- d -glucopyranoside ( 6 ), acacetin-7- O -β- d -glucopyranoside ( 7 ), apigetrin ( 8 ), luteoloside ( 9 ), diosmetin ( 10 ), acacetin ( 11 ), apigenin ( 12 ), luteolin ( 13 ), phlorizin ( 16 ), 1-hydroxy-2- O -β- d -glucopyranosyl-4-allylbenzene ( 19 ), 1- O -β- d -glucopyranosyl-2-hydroxy-4-allylbenzene ( 20 ), chavicol-β- d -glucopyranoside ( 21 ), citrusin C ( 22 ), (2 S )-poncirenin ( 23 ), (6 R ,7 E ,9 R )-9-hydroxymegastigma-4,7-dien-3-one-9- O -β- d -glucopyranoside ( 24 ), rosmarinic acid ( 25 ), methyl rosmarinate ( 26 ), ethyl rosmarinate ( 27 ), nepetoidin B ( 28 ), methyl caffeate ( 29 ), ethyl caffeate ( 30 ), and anisic acid ( 31 ) . Compounds 3 , 4 , 10 , 23 , 27 , 28 , and 30 were isolated from A. rugosa for the first time.…”

Ethnopharmacological Properties and Medicinal Uses of Litsea cubeba

“…The chemical composition of the EO of L. cubeba has been seen to vary from country to country [14,50]. Despite this, the different EOs possess similar properties and exert antimicrobial, antibacterial, antioxidant, and antiparasitic activity [14,53,54,55]. In addition to this, Litsea EO has a peculiar property of insecticidal activity and acts as a repellent against several insects, e.g., cabbage looper ( Trichoplusia ni ), Japanese termite ( Reticulitermes speratus ), mosquito ( Aedes aegypti ), maize weevil ( Sitophilus zeamais ), and red flour beetle ( Tribolium castaneum ), and also possesses nematicidal activity against the pine wood nematode ( Bursaphelenchus xylophilus ) [23,24,56,57].…”

New Dammarane-Type Saponins from Gynostemma pentaphyllum

“…After the detailed spectroscopic analysis and chemical hydrolysis mentioned above, compounds 1 - 6 were proved as novel chemical structures and named as gypenosides CP1-CP6, respectively. The remaining nineteen isolates were identified as 2α,3β,12β,20 S -tetrahydroxydammar-24-ene-3- O -β- d -glucopyranosyl-20- O -[β- d -6- O -acetylglucopyranosyl-(1→2)-β- d -glucopyranoside ( 7 ) [31], gypenoside XLVI ( 8 ) [29], gypenoside LVI ( 9 ) [29], gypenoside LVII ( 10 ) [32], gypenoside LXXVII ( 11 ) [33], gypenoside L ( 12 ) [29], 2α,3β,12β,20 S -tetrahydroxydammar-24-ene-3- O -β- d -glucopyranosyl-20- O -β- d -glucopyranoside ( 13 ) [34], gypenoside XLII ( 14 ) [35], gypenoside Rd ( 15 ) [36] and 2α,3β,20 S -trihydroxydammar-24-ene-3- O -[β- d -glucopyranosyl-(1→2)-β- d -glucopyranosyl]-20- O -[β- d -xylo-pyranosyl-(1→6)-β- d -glucopyranoside] ( 16 ) [37], together with seven flavonoids, quercetin-3- O -α- l -rhamnopyranosyl(1→2)-β- d -galactopyranoside ( 17 ) [38], quercetin-3-neohesperidoside ( 18 ) [39], kaempferol-3- O -α- l -rhamnopyranosyl-(1→2)-β- d -galactopyranoside ( 19 ) [40], kaempferol-3- O -α- l -rhamnopyranosyl-(1→2)-β- d -glucopyranoside ( 20 ) [41], quercetin- 7 - O -β- d -glucoside ( 21 ) [42], kaempferol-7- O -β- d -galactopyranoside ( 22 ) [43], and isorhamnetin-7- O -β- d -glucopyranoside ( 23 ) [44], and two sesquiterpene glucosides, (6 R ,7 E ,9 R )-9-hydroxy-megastigman-4,7-dien-3-one-9- O -β- d -glucopyranoside ( 24 ) [45], and ( E )-4-[3′-(β- d -glucopyranosyloxy)butylidene]-3,5,5-trimethyl-2-cyclohexen-1-one ( 25 ) [46]. The structures of the known compounds were identified by comparing their NMR data with published literature.…”