Meeting report of the 19th Annual International Congress of the International Liver Transplantation Society (Sydney Convention and Exhibition Centre, Sydney, Australia, June 12‐15, 2013)

Abstract

The International Liver Transplantation Society held its annual meeting from June 12 to 15 in Sydney, Australia. More than 800 registrants attended the congress, which opened with a conference celebrating 50 years of liver transplantation (LT). The program included series of featured symposia, focused topic sessions, and oral and poster presentations. This report is by no means all‐inclusive and focuses on specific abstracts on key topics in LT. Similarly to previous reports, this one presents data in the context of the published literature and highlights the current direction of LT. Liver Transpl 20:7–14, 2014. © 2013 AASLD.

Considerations on liver transplantation. concise literature review and update

“…22,23 Splitting livers has become an attractive solution to scarcity of organs, whereby a donated liver is shared between an adult and a pediatric patient, and despite greater technical difficulties associated with such technique compared to whole liver transplantation, results from studies show 82% 10-year survival and 62% 10-year survival in pediatric and adult patients respectively. 6,24 As previously outlined the majority of organ grafts are from deceased donors, which automatically raises the importance of preserving the vitality and viability of the organ till it is transplanted. The main well studied solutions to preserve a liver graft are: The university of Wisconsin solution (UW), the Institute George Lopez solution-1 (IGL-1), Celsior solution, and histidine-tryptophan ketoglutarate preservation solution (HTK), 25 and the UW solution is the standard of care in multiple countries including USA.…”

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“…22,23 Splitting livers has become an attractive solution to scarcity of organs, whereby a donated liver is shared between an adult and a pediatric patient, and despite greater technical difficulties associated with such technique compared to whole liver transplantation, results from studies show 82% 10-year survival and 62% 10-year survival in pediatric and adult patients respectively. 6,24 As previously outlined the majority of organ grafts are from deceased donors, which automatically raises the importance of preserving the vitality and viability of the organ till it is transplanted. The main well studied solutions to preserve a liver graft are: The university of Wisconsin solution (UW), the Institute George Lopez solution-1 (IGL-1), Celsior solution, and histidine-tryptophan ketoglutarate preservation solution (HTK), 25 and the UW solution is the standard of care in multiple countries including USA.…”

Liver Transplantation Update: 2014

“…Despite differences in the rate of graft loss and technical complications between SLT and full size LT, SLT outcomes have improved significantly, and now, the prognosis is almost equivalent to that of full size liver transplantation. 68 …”

“… 69 Recurrence occurs if plasma HCV ribonucleic acid (RNA) remains detectable during transplantation, and approximately 30% of these patients experience accelerated progression to cirrhosis within 5 years of LT. 70 A number of factors associated with more rapid HCV recurrence and complications have been identified, and include high HCV RNA viral load in both serum and liver at the time of LT, genotype 1, female gender, older donor age, steatosis of the graft, degree of human leukocyte antigen (HLA) matching or the IL28b genotype of the donor and the recipient, and de novo donor-specific antibodies. 68 71 …”