Meeting commentary—“Medicines for older adults: Learning from practice to develop patient centric drug products”

Wahlich, John; Stegemann, Sven; Orlu-Gul, Mine

doi:10.1016/j.ijpharm.2013.07.038

Cited by 21 publications

(11 citation statements)

References 22 publications

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“…Acceptability can have a significant impact on adherence, defined by NICE as “the extent to which the patient’s action matches the agreed recommendations” [ 6 ]. The design of a patient-centric drug product for the older population, however, presents a challenge due to the heterogeneous nature of this population [ 7 ]. Co-morbidities and age-related differences, including changes in cognition, motor functions and sensory functions, need to be considered.…”

Section: Introductionmentioning

confidence: 99%

Patient-Centric Medicine Design: Key Characteristics of Oral Solid Dosage Forms that Improve Adherence and Acceptance in Older People

et al. 2020

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Older people represent a very heterogeneous patient population and are the major user group of medication. Age-related changes mean that this population can encounter barriers towards taking medicines orally. The aim of this study was to investigate the characteristics of oral solid dosage forms that contribute to an age appropriate dosage design, with an aim to improve overall medication adherence and acceptance in older people. Fifty-two semistructured interviews were conducted with older people, informal (family) carers, and health and social care professionals. Formulation characteristics impacted three stages of the medication taking process: (1) medication identification and memorability, (2) medication handling and (3) swallowability. Small round tablets (≤7 mm) are least accepted amongst older people and their carers and had a negative impact on all stages. The use of bright, two-coloured preparations and interesting shapes improves identification and further aids memorability of indications and the timing of tablets. Palatability, while useful to enhance swallowability, also has an impact on the visual appeal and memorability of medication. Environmental, patient, medication and disease characteristics also determine preferences for formulation. Developing an age appropriate dosage design for older people, therefore, requires a holistic, patient-centric approach to improve adherence and acceptance.

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Section: Introductionmentioning

confidence: 99%

Patient-Centric Medicine Design: Key Characteristics of Oral Solid Dosage Forms that Improve Adherence and Acceptance in Older People

et al. 2020

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“…Previous priority setting exercises designed to identify older people’s issues have specifically addressed factors relating to medicines, such as barriers to their use, and how to improve their provision [ 8 , 9 ]. However, these exercises have not considered what older people view as important research questions in ageing in healthcare and in a broader sense.…”

Section: Introductionmentioning

confidence: 99%

Older people’s priorities in health and social care research and practice: a public engagement workshop

et al. 2016

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Plain English SummaryA one day public engagement workshop was held to focus on the priorities of older people about research and practice in health and social care. Seventy-five older people from the general public and a variety of backgrounds attended this event to share their views and discuss what should be prioritised. The main aim of this workshop was to identify and prioritise issues that are important to older people that would benefit from further research, as well as create an environment for older people to share ideas and problems related to these important issues. Key priorities brought up by participants included loneliness and isolation, support and training for professional and family carers, post-surgical care, negative perceptions of older people and inequalities related to public services and healthcare. Participants further suggested older people should be actively involved in all stages of the research process.AbstractAs the world’s population ages, there is an increasing need for research that addresses the priorities of older people. A public engagement workshop focusing on the priorities of older people for research and practice in health and social care was attended by seventy-five people aged 70 years and above in London, United Kingdom (UK). The workshop aimed to identify and prioritise issues important to older people that would benefit from further research and act as a platform to promote sharing of ideas and problems related to these important issues. Key priorities emerged including loneliness and isolation, support and training for professional and family carers, post-surgical care, negative perceptions of older people and inequalities related to public services and healthcare. Participants further suggested older people should be actively involved in all stages of the research process.

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“…This sodium salt modification of ibuprofen was reported to be absorbed into plasma more rapidly than conventional ibuprofen and to have comparable tolerability and safety profile (Sörgel et al, 2005). A multiparticulate drug delivery system, such as ``direct to mouth'' granules of ibuprofen sodium, would facilitate the swallowability for geriatric or pediatric population patients suffering from dysphagia (Gandhi et al, 2013;Patel & Dhake, 2011;Patwekar & Baramade;, Sharma & Chaurasia, 2013Stegeman et al, 2011;Wahlich et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Improving the granule strength of roller-compacted ibuprofen sodium for hot-melt coating processing

Lopes

Garsuch

Becker

et al. 2016

International Journal of Pharmaceutics

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Meeting commentary—“Medicines for older adults: Learning from practice to develop patient centric drug products”

Cited by 21 publications

References 22 publications

Patient-Centric Medicine Design: Key Characteristics of Oral Solid Dosage Forms that Improve Adherence and Acceptance in Older People

Patient-Centric Medicine Design: Key Characteristics of Oral Solid Dosage Forms that Improve Adherence and Acceptance in Older People

Older people’s priorities in health and social care research and practice: a public engagement workshop

Improving the granule strength of roller-compacted ibuprofen sodium for hot-melt coating processing

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