Medium term post-bariatric surgery deficit of vitamin B12 is predicted by deficit at time of surgery

Antoine, Darlène; Li, Zhen; Quilliot, Didier; Sirveaux, Marie-Aude; Meyre, David; Mangeon, Alice; Brunaud, Laurent; Guéant, Jean‐Louis; Guéant-Rodríguez, Rosa-María

doi:10.1016/j.clnu.2020.04.029

Cited by 13 publications

(7 citation statements)

References 31 publications

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“…B12 every 1-3 months is adequate as a maintenance treatment to keep serum B12 concentrations within the reference range [18,78]. Lowered serum concentrations of vitamin B12 are unlikely to be corrected by using 3-6 µg/day B12 from food supplements or high oral B12 (1000 µg) provided once weekly [30,73,79]. High dose oral and i.m.…”

Section: Vitamin B12 Deficiency In the Medical Literaturementioning

confidence: 99%

Diagnosis, Treatment and Long-Term Management of Vitamin B12 Deficiency in Adults: A Delphi Expert Consensus

Obeid,

Andrès,

Češka

et al. 2024

JCM

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Background/Objectives: Vitamin B12 deficiency can cause variable symptoms, which may be irreversible if not diagnosed and treated in a timely manner. We aimed to develop a widely accepted expert consensus to guide the practice of diagnosing and treating B12 deficiency. Methods: We conducted a scoping review of the literature published in PubMed since January 2003. Data were used to design a two-round Delphi survey to study the level of consensus among 42 experts. Results: The panelists agreed on the need for educational and organizational changes in the current medical practices for diagnosing and treating B12 deficiency. Recognition of clinical symptoms should receive the highest priority in establishing the diagnosis. There is agreement that the serum B12 concentration is useful as a screening marker and methylmalonic acid or homocysteine can support the diagnosis. Patient lifestyle, disease history, and medications can provide clues to the cause of B12 deficiency. Regardless of the cause of the deficiency, initial treatment with parenteral B12 was regarded as the first choice for patients with acute and severe manifestations of B12 deficiency. The use of high-dose oral B12 at different frequencies may be considered for long-term treatment. Prophylactic B12 supplementation should be considered for specific high-risk groups. Conclusions: There is a consensus that clinical symptoms need to receive more attention in establishing the diagnosis of B12 deficiency. B12 laboratory markers can support the diagnosis. The severity of clinical symptoms, the causes of B12 deficiency, and the treatment goals govern decisions regarding the route and dose of B12 therapy.

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Section: Vitamin B12 Deficiency In the Medical Literaturementioning

confidence: 99%

Diagnosis, Treatment and Long-Term Management of Vitamin B12 Deficiency in Adults: A Delphi Expert Consensus

Obeid,

Andrès,

Češka

et al. 2024

JCM

Self Cite

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“…La obesidad como problemática mundial de salud se ha incrementado significativamente, siendo la segunda causa de muerte luego del tabaquismo (1). La obesidad , y particularmente la obesidad mórbida (definida a través de un valor de IMC de 40 kg/m2 o más), se asocia con otras comorbilidades como la resistencia a la insulina, diabetes tipo 2 (DM2), hipertensión arterial (HTA), dislipemia, hígado graso no alcohólico, enfermedad renal, enfermedad cardiovascular y eventos como la muerte prematura (2)(3)(4). La prevalencia mundial de sobrepeso (IMC 25-30 kg/m2) y obesidad (IMC>30 Kg/m2) y el número de personas afectadas ha aumentado en todos los grupos de edad y seguirá aumentando en el próximo decenio (5).…”

Section: Introductionunclassified

Evolution of micronutrient status in morbidly obese adults undergoing bariatric surgery

Néspola,

Acosta Sero

2024

SCT Proceedings in Interdisciplinary Insights and Innovations

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Background: Obesity as a global health problem has increased significantly. It is a chronic disease associated with significant morbidity and mortality. Since conventional treatments are not enough, bariatric surgery has had a considerable efficacy in relation to weight loss and reduction in the prevalence of comorbidities associated with it, however, the micronutrient deficits already existing in obesity may be altered even after the surgical intervention. The aim of this study will be to describe the behavior of micronutrient deficits in adults undergoing laparoscopic vertical sleeve gastrectomy.). Material and methods: An observational, retrospective, analytical and longitudinal design with a cross-sectional component, of an adult population between 21 and 70 years of age, both biological sexes, with a diagnosis of morbid obesity (BMI) greater than or equal to 40 kg/m) submitted to a GVM, followed up for a minimum of 12 months post-surgery. The data of interest were weight loss, the presence of anemia, and deficiency of folic acid, vitamin B12, and vitamin D, preoperatively and at 3.6 and 12 months post- surgery, as well as the trajectory of these parameters over time according to sex. Results: 268 patients were included, 54% (n= 145) were men, the mean age at the time of surgery was 43.4 years. Most had a history of obesity from one of their parents and developed obesity in childhood or adolescence. The percentage of patients with a percentage of excess weight lost (PEPP) greater than or equal to 50% was 86.9% at 12 months. The prevalence of anemia was higher at 12 postoperative months and the deficiency of folic acid, vitamin B12 and vitamin D predominated at the preoperative moment, steadily reducing from 3 to 12 postoperative months. No differences were observed between sexes. Conclusion: Bariatric surgery continues to be an effective technique of choice for sustained and rapid weight loss compared to conventional treatments for morbid obesity. It is necessary to monitor the status of micronutrients in the long term, encourage and motivate the use of supplementation together with a long-term individualized interdisciplinary follow-up, as nodal requirements for the improvement and/or resolution of deficits

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“…However, it should be noted that not only people with obesity were vulnerable, but also those who underwent metabolic surgery (MS) and presented micronutrient deficiency caused by the surgical technique and lack of multivitamin supplementation (Albaugh et al, 2021;Antoine et al, 2021;Carabotti et al, 2021;Chamberlain et al, 2021). These are a concern for this population since deficiencies such as vitamin D have been associated with the presence of anxiety, depression and suicidal ideation (khan et al, 2022;Kim et al, 2020;Menon et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Modelo de bienestar en salud, insatisfacción y estrés laboral en enfermería ante el COVID-19

González-Sánchez,

López-Ramos,

Lara-Esquivel

et al. 2023

Horiz. Interdisc. J.

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Antecedentes: La pandemia por el COVID-19 acentuó las grandes carencias e inequidades en el sector salud en México, donde el bienestar en salud del personal de enfermería se vio alterado por un aumento en la insatisfacción y estrés laboral debido a nuevos protocolos de atención, sobrecarga de trabajo, escasez de recursos tanto humanos como materiales, así como la pérdida de compañeros y familiares. Objetivo: Probar un modelo de bienestar en salud a partir de las condiciones laborales, satisfacción y estrés laboral en profesionales de enfermería durante la primera ola de COVID-19 en Tijuana, B.C. Método: Estudio descriptivo correlacional realizado de junio 2021 a mayo 2022. Se aplicaron instrumentos de medición a 325 profesionales para evaluar su bienestar en salud, satisfacción laboral, estrés laboral, actividad física y percepción de aspectos relacionados con la pandemia por COVID-19. Se realizó estadística descriptiva, comparaciones de medias y correlaciones de Pearson y Spearman para construir un modelo de análisis de ruta (Path Analysis). Resultados: El modelo mostró un adecuado ajuste: Chi-cuadrado (χ2)=50.085 (43), p=0.213; Error de Aproximación Raíz-Media-Cuadrada (RMSEA)=0.023; Índice de Bondad de Ajuste (GFI)=0.978; Índice de Ajuste Comparativo (CFI)=0.994; Índice de Ajuste Normado Parsimonioso (PNFI)=0.551; Criterio de Información de Akaike (AIC)=146.08. Se demostró que el estrés (Zβ=-0.470) y la percepción de decepción laboral (Zβ=-0.068) tienen un efecto sobre el bienestar en salud mientras que la satisfacción laboral (Zβ=0.370) y percepción de protección laboral (Zβ=0.320) tienen un efecto positivo. Conclusión: La satisfacción laboral, estrés laboral, percepción de protección laboral y percepción de decepción laboral predicen significativamente el bienestar en salud en el personal de enfermería.

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Medium term post-bariatric surgery deficit of vitamin B12 is predicted by deficit at time of surgery

Cited by 13 publications

References 31 publications

Diagnosis, Treatment and Long-Term Management of Vitamin B12 Deficiency in Adults: A Delphi Expert Consensus

Diagnosis, Treatment and Long-Term Management of Vitamin B12 Deficiency in Adults: A Delphi Expert Consensus

Evolution of micronutrient status in morbidly obese adults undergoing bariatric surgery

Modelo de bienestar en salud, insatisfacción y estrés laboral en enfermería ante el COVID-19

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