Abstract:The Contegra conduit and homograft demonstrate similar mid-term outcomes in children. Smaller conduit size is associated with higher graft failure and mortality.
“…Vegetation and conduit stenosis were commonly observed in failed BJV conduits. The worst situation occurred in BJV conduit obstruction, which usually required emergency surgery or extracorporeal membrane oxygenation support (15), and was considered one of the main reasons for late mortality (16). In terms of the other possible risk factors for BJV conduit failure, our study did not find that either a younger age (≤1 year) (17) or a small-size conduit (≤14 mm) (18) was a significant risk factor, possibly because we used a different study population and a larger BJV conduit size than other studies.…”
Background: Bovine jugular vein (BJV) conduits are widely applied for surgical reconstruction of the right ventricular outflow tract (RVOT). However, relevant studies of valve failure rates and the related risk factors are limited in China. The aim of this study was to assess the BJV prognosis after medium-to long-term follow-up. Methods: Fifty-three hospital patients implanted with BJV conduits from January 2002 to December 2013 were recruited. Patient information and follow-up prognosis were reviewed retrospectively. Conduit stenosis and failure as well as endocarditis were diagnosed. Results: The total person years was 345.5, and the median follow-up time was 6.3 years. Early mortality occurred in two patients, and there was no late mortality. BJV conduit failure occurred in 15 patients (29.4%) due to severe stenosis (n=10), stenosis plus regurgitation (n=3), and regurgitation alone (n=2). The proportion of patients who were free of BJV conduit failure at 1, 3, 5, and 7 years was 98.0%, 85.8%, 76.8%, and 62.1%, respectively. There were nine cases of endocarditis (17.0%). Multivariate logistic regression analysis showed that endocarditis was a significant risk factor associated with BJV conduit failure (OR: 6.735; 95% CI: 1.348-33.647). Conclusions: The durability of BJV conduits was suboptimal after a mid-term follow-up period.Endocarditis was found to be a significant risk factor that accelerates BJV conduit deterioration.
“…Vegetation and conduit stenosis were commonly observed in failed BJV conduits. The worst situation occurred in BJV conduit obstruction, which usually required emergency surgery or extracorporeal membrane oxygenation support (15), and was considered one of the main reasons for late mortality (16). In terms of the other possible risk factors for BJV conduit failure, our study did not find that either a younger age (≤1 year) (17) or a small-size conduit (≤14 mm) (18) was a significant risk factor, possibly because we used a different study population and a larger BJV conduit size than other studies.…”
Background: Bovine jugular vein (BJV) conduits are widely applied for surgical reconstruction of the right ventricular outflow tract (RVOT). However, relevant studies of valve failure rates and the related risk factors are limited in China. The aim of this study was to assess the BJV prognosis after medium-to long-term follow-up. Methods: Fifty-three hospital patients implanted with BJV conduits from January 2002 to December 2013 were recruited. Patient information and follow-up prognosis were reviewed retrospectively. Conduit stenosis and failure as well as endocarditis were diagnosed. Results: The total person years was 345.5, and the median follow-up time was 6.3 years. Early mortality occurred in two patients, and there was no late mortality. BJV conduit failure occurred in 15 patients (29.4%) due to severe stenosis (n=10), stenosis plus regurgitation (n=3), and regurgitation alone (n=2). The proportion of patients who were free of BJV conduit failure at 1, 3, 5, and 7 years was 98.0%, 85.8%, 76.8%, and 62.1%, respectively. There were nine cases of endocarditis (17.0%). Multivariate logistic regression analysis showed that endocarditis was a significant risk factor associated with BJV conduit failure (OR: 6.735; 95% CI: 1.348-33.647). Conclusions: The durability of BJV conduits was suboptimal after a mid-term follow-up period.Endocarditis was found to be a significant risk factor that accelerates BJV conduit deterioration.
“…В некоторых работах, однако, отмечена довольно высокая частота осложнений, наиболее частыми среди которых являются дистальные стенозы кондуита, об-условливающие также дилатацию проксимальной части ксеноимплантата с развитием аневризм или псевдоанев-ризм [13,14,38,[40][41][42][43][44][45][46][47][48].…”
“…[42] сообщают о суправальвулярных стенозах, которые потребовали повторных вмешательств у 15,8% у пациентов с Contegra со средней продолжительностью наблюдения 18 мес. В метаанализе [42] и ряде других работ [43,44] было отмечено, что наиболее частой причиной дисфункций кондуита, развивающихся в течение первого года после операции, является стеноз дистального анастомоза, обусловленный гиперплазией псевдоинтимы. Это осложнение развивается тем чаще, чем младше возраст пациента и меньше диаметр кондуита [45].…”
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