Medico-Genetic Diagnosis of Hereditary Predisposition to Noncarrying of Pregnancy and Reproductive Losses

Руденко, І. В.; Lihachov, V. K.; Mischenko, V. P.; Golubenko, M. Y.; Shymanska, Y. Y.

doi:10.26724/2079-8334-2018-2-64-75-77

WOMAB

2018

DOI: 10.26724/2079-8334-2018-2-64-75-77

|View full text |Cite

Medico-Genetic Diagnosis of Hereditary Predisposition to Noncarrying of Pregnancy and Reproductive Losses

І. В. Руденко

V. K. Lihachov

V. P. Mischenko

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2019

2021

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…During pregnancy, the body of a healthy woman undergoes psychological changes that contribute to the successful carrying and prepare it for future childbirth and motherhood [1,6,10]. In women who experience failures at the stage of fertilization or during pregnancy (not asso-ciated with a hereditary predisposition to miscarriage [21]) can develop psycho-emotional stress as a result of prolonged negative emotions [6,12].…”

mentioning

confidence: 99%

The Relationship Between Changes in Immune Status and Disorders of Psycho-Emotional State in Pregnant Women With in Vitro Fertilization and Threatened Premature Birth

Ліхачов

Shymanska

Dobrovolska

2021

Med. and Ecol. probl.

View full text Add to dashboard Cite

Women who experience failures at the stage of fertilization or during pregnancy can develop psycho-emotional stress as a result of prolonged negative emotions with a high level of anxiety, neurotic conflict, often accompanied by a complicated pregnancy. The international academic literature discusses a possible link between high levels of anxiety and depression, on the one hand, and changes in the state of the immune system, on the other. The aim of the research was to identify the relationship between psycho-emotional changes in pregnant women with in vitro fertilization and threatened premature birth and changes in their immune status. The psycho-emotional state was studied in 60 women in the second trimester of pregnancy with a history of infertility, whose pregnancy resulted from IVF, and with threatened premature birth. As a control group, 20 healthy women with a physiological course of pregnancy were examined. The levels of trait (TA) and state anxiety (SA), as well as the degree of depressive disorders in these women, were assessed. In parallel, the levels of pro- and anti-inflammatory cytokines and the state of cellular-humoral immunity were determined, looking for correlations between these indicators, the levels of anxiety, and manifestations of depression in the examined patients. Pregnant women with in vitro fertilization and threatened premature birth revealed high levels of state (53.3% of women) and trait (56.8% of women) anxiety; 70% of pregnant women are dominated by euphoric, anxious, and depressive types of the psychological component of gestational dominant; 33.3% of the examined women demonstrated a state of mild and masked depression. Correlations were found between an increase in SA and TA scores and an elevated concentration of TNF-α and INF-γ, as well as between an increase in the level of TNF-α and the score of depression. A connection was found between a decrease in the number of T-helpers and an increase in the TA score in the examined patients.

show abstract

mentioning

confidence: 99%

The Relationship Between Changes in Immune Status and Disorders of Psycho-Emotional State in Pregnant Women With in Vitro Fertilization and Threatened Premature Birth

Ліхачов

Shymanska

Dobrovolska

2021

Med. and Ecol. probl.

View full text Add to dashboard Cite

show abstract

Changes of Psycho-Emotional State in the Infertile Pregnant Females Due to the Anamnesis and Ivf

et al. 2019

View full text Add to dashboard Cite

Introduction: During pregnancy in the body of a healthy woman there are physiological and psychological changes that contribute to the bearing a child and prepare the female for future labour and motherhood. In women who experience failure at the stage of fertilization or during pregnancy, as a result of prolonged negative emotional states, psycho-emotional stress develops. The aim of the research was to study the psycho-emotional state of women with infertility in history, whose pregnancy resulted from extracorporal fertilization (IVF), and to develop methods for reducing their anxiety. Materials and methods: At the first stage, the initial psycho-emotional state of 60 women in the second trimester, whose pregnancy resulted from IVF (Group I), was studied; the control group consisted of 20 healthy women with a physiological course of pregnancy (Group II). At the second stage, 10 art therapy exercises with a requestioning of pregnant women from Group I were conducted for improving their psycho-emotional state. Results: Women of Group I had a high level of both situational anxiety (SA) and the personal one (PA). The prevalent type of the psychological component of gestational dominant was anxiety and euphoric types (58.3%). In one third of women with burdened gynecological history examined mild or masked depression was diagnosed. 43 pregnant women from Group I used a method of psychocorrection – art therapy, which included colouring “antistress” pictures of perinatal topic, making flowers from paper and creating a collage of dreams. Conclusions: After the art therapy course, a high level of SA (from 46.5% to 7.0%) and OA (from 48.8% to 32.6%) decreased, the index of the optimal type of the psychological component of gestational dominant increased from 25.6% to 53.5%. The number of women without depression increased from 62.8% to 93%.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Medico-Genetic Diagnosis of Hereditary Predisposition to Noncarrying of Pregnancy and Reproductive Losses

Cited by 2 publications

References 0 publications

The Relationship Between Changes in Immune Status and Disorders of Psycho-Emotional State in Pregnant Women With in Vitro Fertilization and Threatened Premature Birth

The Relationship Between Changes in Immune Status and Disorders of Psycho-Emotional State in Pregnant Women With in Vitro Fertilization and Threatened Premature Birth

Changes of Psycho-Emotional State in the Infertile Pregnant Females Due to the Anamnesis and Ivf

Contact Info

Product

Resources

About