Medicine has always been “Modern” and “Scientific” from ancient times to the present day

Teppone, Mikhail

doi:10.1016/j.joim.2019.03.008

Cited by 7 publications

(4 citation statements)

References 36 publications

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“…Internationally, consumers have great concern for using natural resources as an adjunct to pharmaceuticals against many ailments [ 6 ]. The thought of food as a therapeutic agent can be traced back up to the era of Hippocrates, the father of medicine [ 7 ].…”

Section: Nutraceuticals and Pharma Foodsmentioning

confidence: 99%

Unveiling the Chemistry of Citrus Peel: Insights into Nutraceutical Potential and Therapeutic Applications

Munir,

Yaqoob,

Awan

et al. 2024

Foods

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The recent millennium has witnessed a notable shift in consumer focus towards natural products for addressing lifestyle-related disorders, driven by their safety and cost-effectiveness. Nutraceuticals and functional foods play an imperative role by meeting nutritional needs and offering medicinal benefits. With increased scientific knowledge and awareness, the significance of a healthy lifestyle, including diet, in reducing disease risk is widely acknowledged, facilitating access to a diverse and safer diet for longevity. Plant-based foods rich in phytochemicals are increasingly popular and effectively utilized in disease management. Agricultural waste from plant-based foods is being recognized as a valuable source of nutraceuticals for dietary interventions. Citrus peels, known for their diverse flavonoids, are emerging as a promising health-promoting ingredient. Globally, citrus production yields approximately 15 million tons of by-products annually, highlighting the substantial potential for utilizing citrus waste in phyto-therapeutic and nutraceutical applications. Citrus peels are a rich source of flavonoids, with concentrations ranging from 2.5 to 5.5 g/100 g dry weight, depending on the citrus variety. The most abundant flavonoids in citrus peel include hesperidin and naringin, as well as essential oils rich in monoterpenes like limonene. The peel extracts exhibit high antioxidant capacity, with DPPH radical scavenging activities ranging from 70 to 90%, comparable to synthetic antioxidants like BHA and BHT. Additionally, the flavonoids present in citrus peel have been found to have antioxidant properties, which can help reduce oxidative stress by 30% and cardiovascular disease by 25%. Potent anti-inflammatory effects have also been demonstrated, reducing inflammatory markers such as IL-6 and TNF-α by up to 40% in cell culture studies. These findings highlight the potential of citrus peel as a valuable source of nutraceuticals in diet-based therapies.

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Section: Nutraceuticals and Pharma Foodsmentioning

confidence: 99%

Unveiling the Chemistry of Citrus Peel: Insights into Nutraceutical Potential and Therapeutic Applications

Munir,

Yaqoob,

Awan

et al. 2024

Foods

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“…On the other hand, tisanes or herbal teas are infusions made from leaves, bark, roots, flowers, berries and seeds of other medicinal herbs or spices (Chandrasekara & Shahidi, 2018), which may be made homemade or purchased in the markets as simple (a single herb) or composed (blend of two or more herbs) products. In several countries, these beverages are the base of folk medicine systems and primary care, and are considered effective and safe when used rationally (Ren et al, 2019;Teppone, 2019).…”

Section: Introductionmentioning

confidence: 99%

Correlation of polyphenol content and antioxidant capacity of selected teas and tisanes from Brazilian market

Alves

Rodrigues

Thomaz

et al. 2020

Braz. J. Food Technol.

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In this work, it was evaluated the phenolic content, redox behavior and antioxidant capacity of several selected teas and tisanes from Brazilian market. The samples were classified as simple (single herb) or composed (blend of two or more herbs). In addition, complementary multivariate statistical approaches were used to identify the correlation and interdependence between the amount of major phytocomponents, such as phenols and flavonoids, as well as the antioxidant activity of the products. Results showed that the total polyphenol and total flavonoid concentrations are correlated to thermodynamic feasibility of reactive oxygen species reduction. The statistical modeling differentiated the results datasets in principal components, whose flavonoid content presented itself as the main parameter to segregate data between simple and composed products. On the other hand, the whole polyphenol content, in both teas and tisanes, was more relevant regarding their antioxidant capacity than the flavonoids content. Considering that the manufactures do not display the real amount of each herb in the labels of the composed products, it was not possible to confirm whether the blends of several species lead to a substantial enhancement on their antioxidant capacity. Furthermore, the redox profile and overall polyphenol content suggest that the consumption of green and black teas as well as traditional yerba mate may be worthwhile in preventing ailments associated with oxidative stress in Brazilian population. Notwithstanding, further clinical studies are required to validate this hypothesis.

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“…It is an important point in the history of science, in particular medicine. In the ancient and medieval eras, there was a holistic view to science in most parts of the civilized world . Because of this paradigm, most of the great scientists were polymaths and experts in many branches of science, like medicine, chemistry (Alchemy), pharmacy, philosophy, mathematics, and astronomy.…”

mentioning

confidence: 99%

“…After the Renaissance (approximately the 16th century), this holistic paradigm was replaced slowly by an atomistic and molecular view, caused by progress of modern science and technology. Following this change in the paradigm of science, including medicine, the world was going to be specialized more and more, in particular during last century . But another thinking is going to be formed that this specializing is not completely ideal, and the holistic view could be beneficial to better understanding the world and science.…”

mentioning

confidence: 99%

Michael Servetus, Doctor of Medicine—Reply

Zargaran

2022

JAMA Cardiol

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To the Editor Zargaran 1 should be congratulated for his recent article in JAMA Cardiology reviewing the history of pulmonary circulation and going so far as the ancient Sassanid era to show that some ideas of pulmonary circulation predated in a thousand years the presentation of the lesser circulation in Miguel Serveto's "Christianismi Restitutio." In the article, Michael Servetus is presented as a "Spanish theologian," 1 and although Servetus is mainly known as a religious reformer with a dramatic end, burned at the stake in Geneva, he was actually a quite versatile writer interested in medicine, mathematics, astrology, and geography. 2 He learned medicine in Paris from Johann Guenther von Andernach, MD, and Jacobus Sylvius, MD, sharing dissection time with Andreas Vesalius, MD. 3 Then, he practiced medicine in Charlieu, France (1539-1541), and Vienne, France (1941-1953, and published a successful medical book, Syruporum Universa Ratio, that went through 6 editions. 2 In this book, he follows the predominant Galenic theory.Michael Servetus was a universal man who believed that all disciplines are deeply interrelated. A good model in our super specialized world!

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Medicine has always been “Modern” and “Scientific” from ancient times to the present day

Cited by 7 publications

References 36 publications

Unveiling the Chemistry of Citrus Peel: Insights into Nutraceutical Potential and Therapeutic Applications

Unveiling the Chemistry of Citrus Peel: Insights into Nutraceutical Potential and Therapeutic Applications

Correlation of polyphenol content and antioxidant capacity of selected teas and tisanes from Brazilian market

Michael Servetus, Doctor of Medicine—Reply

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