The COVID-19 pandemic has stretched health care resources to the point of crisis worldwide. It is considered the worst global emergency since World War II and has intensely shaken health systems, economies, and societies. The pandemic began in China back in December 2019 with rapid and extensive international spread, and a mortality rate of more than three million people to date, overwhelming hospitals, mortuaries, and cemeteries. The short-term impact on people takes the form of anxiety about health and livelihoods, and restrictive adjustments. Healthcare workers also carry the physical and psychological burden of working through further pandemic peaks having experienced the first wave. Although there has been growing recognition of the importance of human factors (HF), skills and ergonomics in delivering high quality care in the complex environment of the intensive care unit (ICU), the pandemic has sharply accelerated their application.