Medicinal plants used in Jeddah, Saudi Arabia: Phytochemical screening

Alqethami, Afnan; Aldhebiani, Amal Y.

doi:10.1016/j.sjbs.2020.11.013

Cited by 44 publications

(32 citation statements)

References 21 publications

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“…The same study was shown by Hosseinzadeh et al which the water and ethanol extract of Pimpinella anisum L. significantly increased milk production by about 68.1% and 81% more than the control group 10 , and so does with fenugreek which can increase milk production 32 . Some of the phytochemical components contained in these plants are alkaloid, flavonoid, and saponin 33 , which in molecular analysis, this type of phytochemical can interact with estrogen receptors so that it can increase milk production 34 . This fact could be attributed that the molecular structure of flavonoids has similarities with the natural estrogen hormone along with other steroid hormone and their antagonist 35 .…”

Section: Discussionmentioning

confidence: 99%

Carica papaya leaf ethanol extract effect on milk volume, β-casein gene (Csn2) expression, β-casein levels, and milk total protein levels

Herawati¹,

Kalsum²,

Wiyasa³

et al. 2022

Pharm Sci Asia

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The phytochemical compounds contained in papaya leaves are known to have a galactopoietic effect. This study aims to analyze the effect of ethanol extract of Carica papaya leaves on β-casein gene expression, βcasein levels, total protein, and milk volume. This in vivo was an experimental study including a posttest control group that was conducted on one control group and three treatment groups. Each group consisted of six lactating rats. The control group rats were given ordinary food, while the treatment group rats, D1, D2, and D3, were given ethanol extract of Carica papaya leaves with the dose of 0.95 mg, 1.9 mg, and 3.8 mg/200 g Body weight (BW)/ day, respectively, from day 1 to day 13 of lactation. On day 14, all of the rats were sacrificed. Breastmilk volume taken from all breasts of lactating rats was measured individually in milliliters, β-casein gene expressions in the mammary tissues were measured using reverse transcription polymerase chain reaction (RT-PCR), while serum β-casein levels were measured using ELISA, and total protein was measured using bicinchoninic acid (BCA) protein assay. Statistical analysis was carried out using one-way ANOVA, Tukey test, and Games-Howell test at 95% confidence level. Milk volume, β-casein gene expression, β-casein levels, and total protein levels of all treatment rat groups were significantly higher than the control group (p<0.05). The increases of all parameters were consistent; the most effective dose was 1.9 mg/200g BW. Carica papaya leaf ethanol extract can increase milk volume, β-casein gene (Csn2) expression, β-casein levels, and total protein levels.

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Section: Discussionmentioning

confidence: 99%

Carica papaya leaf ethanol extract effect on milk volume, β-casein gene (Csn2) expression, β-casein levels, and milk total protein levels

Herawati¹,

Kalsum²,

Wiyasa³

et al. 2022

Pharm Sci Asia

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“…This makes them an important natural source for usage in either traditional or conventional medicine. However, their values can be specified by the diversity of their phytochemical constituents which produce a certain physiological effect on the organism (29). These phytochemicals may be distinguished in several ways, which are based on their biosynthetic origin, solubility properties, and the presence of key chemical groups (30).…”

Section: Discussionmentioning

confidence: 99%

Antioxidant Activities of Eremurus spectabilis M. Bieb. Extracts and Sulfur Compounds

Bayrak¹,

Yanardağ²

2021

ejb

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Objective: Eremurus spectabilis M. Bieb. is grown in East and Southeast Mediterranean regions of Turkey, and is commonly used as an edible plant in these regions. The aim of the current study was to determine the antioxidant activities of different E. spectabilis M. Bieb. extracts and some sulfur compounds. Materials and Methods:In this study, the antioxidant activities of aqueous, ethanolic, and ethyl acetate extracts of E. spectabilis M. Bieb. and sulfur compounds (α-lipoic acid, cysteamine, cysteine, diallyl sulfide, glutathione, homocysteine, N-acetyl cysteine, vitamin U and 1,4-dithioerythritol) were assessed in several antioxidant tests. These tests included reducing power, cupric ion reducing antioxidant capacity, 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging, 2,2-diphenyl-1-picrylhydrazyl radical scavenging, N,N-dimethyl-4-phenylenediamine dihydrochloride radical scavenging, superoxide anion radical scavenging, hydroxyl radical scavenging, metal chelating activities and ferric ion reducing antioxidant power. The phytochemical profiles and total phenolic and flavonoid contents of all extracts were investigated.Results: It was found out that the antioxidant activities of all the extracts and sulfur compounds generally increased with concentration increases, the highest antioxidant activity was found in ethyl acetate extract, while the aqueous extract was found to have the lowest antioxidant activity. Diallyl sulfide was found to have the highest antioxidant activity, whereas vitamin U had the lowest antioxidant activity. It was observed that all extracts of E. spectabilis M. Bieb. and the sulfur compounds showed antioxidant activity. Conclusion:The E. spectabilis M. Bieb. and sulfur compounds investigated in this study could be considered as a source of antioxidants.

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“…Phản ứng định tính thành phần hóa học alkaloid, flavonoid, steroid, terpenoid, cumarin của cao chiết từ phần rễ của loài W. x "Bristol ruby" được thực hiện dựa trên phản ứng kết tủa và tạo màu của Alqethami và cộng sự (2021) [14], định tính saponin và glycoside tim được thực hiện theo phương pháp của Traore và cộng sự (2015) [15]. Hòa tan cao chiết trong 2 mL DMSO 10% để thu dịch chiết, sử dụng cho các phản ứng định tính.…”

Section: Phương Pháp địNh Tính Thành Phần Hóa Họcunclassified

Nghiên Cứu Thành Phần Hóa Học Và Hoạt Tính Sinh Học Của Cao Chiết Loài Weigela X “Bristol Ruby”

Hùng¹,

Dung²

2022

TNUJST

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Trong nghiên cứu này, cao chiết ethanol từ phần rễ của loài W. x “Bristol ruby” đã được định tính thành phần hóa học và đánh giá hoạt tính sinh học. Kết quả định tính cho thấy, sự có mặt của flavonoid, terpenoid, coumarin và saponin triterpene, nhưng không có alkaloid, steroid và glycoside tim. Cao chiết ethanol từ phần rễ của loài W. x “Bristol ruby” có hoạt tính kháng oxy hóa với giá trị EC50 là 71,94 µg/mL. Hoạt tính gây độc trên dòng tế bào ung thư đại trực tràng CT26 cho thấy cao chiết ethanol từ phần rễ của loài W. x “Bristol ruby” có hoạt tính ức chế tế bào ung thư với giá trị IC50 là 11,83 µg/mL khi so sánh với đối chứng dương 5-Fluorouracil với giá trị IC50 là 36,76 µg/mL. Nghiên cứu đề xuất sự cần thiết tiếp tục tiến hành phân lập các hợp chất tinh sạch có trong cao chiết ethanol từ phần rễ của loài W. x “Bristol ruby” và đánh giá hoạt tính sinh học của các hợp chất này.

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Medicinal plants used in Jeddah, Saudi Arabia: Phytochemical screening

Cited by 44 publications

References 21 publications

Carica papaya leaf ethanol extract effect on milk volume, β-casein gene (Csn2) expression, β-casein levels, and milk total protein levels

Carica papaya leaf ethanol extract effect on milk volume, β-casein gene (Csn2) expression, β-casein levels, and milk total protein levels

Antioxidant Activities of Eremurus spectabilis M. Bieb. Extracts and Sulfur Compounds

Nghiên Cứu Thành Phần Hóa Học Và Hoạt Tính Sinh Học Của Cao Chiết Loài Weigela X “Bristol Ruby”

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