Medicinal plants used as antidiarrheal agents in the lower Mekong basin

Chassagne, François

doi:10.1016/b978-0-323-90999-0.00015-x

Cited by 2 publications

(1 citation statement)

References 153 publications

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“…Psidium guajava is one of the most used antidiarrheal plant species in tropical countries. Different parts of guava tree are used as remedies against diarrhea in Latin America (e.g., Panama, Mexico, Peru, Caribbean), in Asia (e.g., India, China, Bangladesh, Thailand), and in Africa (e.g., Niger, Ghana, Congo, South Africa) (Chassagne, 2022;Gutiérrez et al, 2008). From a pharmacological perspective, guava leaf demonstrated antibacterial activity against Vibrio cholerae, Shigella flexneri and diarrheagenic Escherichia coli (Birdi et al, 2010).…”

Section: Benefit-risk Balance Of the Most Cited Treatmentsmentioning

confidence: 99%

Polynesian medicine used to treat diarrhea and ciguatera: An ethnobotanical survey in six islands from French Polynesia

Chassagne

Butaud

Torrente

et al. 2022

Journal of Ethnopharmacology

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Section: Benefit-risk Balance Of the Most Cited Treatmentsmentioning

confidence: 99%

Polynesian medicine used to treat diarrhea and ciguatera: An ethnobotanical survey in six islands from French Polynesia

Chassagne

Butaud

Torrente

et al. 2022

Journal of Ethnopharmacology

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Ethnobotany, phytochemistry, and biological activities of Psidium guajava in the treatment of diarrhea: a review

Liu,

Jullian,

Chassagne

2024

Front. Pharmacol.

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Psidium guajava: is a tropical tree that is widely used in traditional medicine, especially for treating diarrhea. While P. guajava has been the subject of numerous reviews, none have specifically examined its ethnobotany, pharmacology, and phytochemistry in relation to its antidiarrheal activity. This review aims to summarize the evidence of effectiveness and safety of P. guajava in the treatment of diarrhea. Literature searches were conducted through Web of Science, PubMed, and ScienceDirect by using keywords “Psidium guajava” and “diarrhea” in October 2022. A total of 189 studies were included in this review. P. guajava is widely used in traditional medicine in 44 countries. Decoction and oral were the most represented method of preparation and administration, respectively, while leaves represented the most frequently cited part of the plant. Around 27 antidiarrheal or antibacterial compounds have been isolated and identified, including benzophenone glycosides, terpenes, polysaccharides, phenols, and flavonoids. This article presents ethnobotanical and pharmacological evidence for the efficacy of P. guajava leaves in the treatment of diarrhea and provides reference information for further investigation of this plant. However, despite the large number of publications on the topic, there are still some questions to answer: are quercetin and its glycosides the only ones to act as antidiarrheal agents? What is the mechanism of action of P. guajava antidiarrheal compounds? are the use of guava leaves safe in all types of populations including children, and at what dosage? To answer these questions, more complete phytochemical studies and systematic clinical trials are needed.

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Medicinal plants used as antidiarrheal agents in the lower Mekong basin

Cited by 2 publications

References 153 publications

Polynesian medicine used to treat diarrhea and ciguatera: An ethnobotanical survey in six islands from French Polynesia

Polynesian medicine used to treat diarrhea and ciguatera: An ethnobotanical survey in six islands from French Polynesia

Ethnobotany, phytochemistry, and biological activities of Psidium guajava in the treatment of diarrhea: a review

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