Medicinal Plants in the Indian Traditional Medicine and Current Practices

Insights into Metabolites Profiling and Pharmacological Investigation of Aconitum heterophyllum wall ex. Royle Stem through Experimental and Bioinformatics Techniques

“…Natural products (NPs) are receiving unprecedented attention around the globe owing to bioactive phytochemical constituents especially in the anti-infection and antitumor areas. About 67% effective cancer drugs are derived from NPs such as vincristine and vinblastine from various plant species. ,, …”

“…About 67% effective cancer drugs are derived from NPs such as vincristine and vinblastine from various plant species. 5,64,65 The plants of the genus aconitum chemically include steroids, glycosides, alkaloids, and flavonoids. Diterpenoid alkaloids are considered toxic as well as the main efficient anticancer components of these plants.…”

“…4 These medicinal plants, since time immemorial, have been exploited as a source of novel pharmacophores in the production of lead compounds in the pharmaceutical industry. 5,6 The FDA finds that most approved drugs have pharmacophore links to natural products. These comprise antihypertensive drugs like enalapril and captopril, as well as antitumor agents camptothecin, taxol, and docetaxel.…”

“…They are an important source of novel drugs for the prevention and treatment of various diseases. − A huge number of metabolites of varying structure and abundance, which play important roles in plant growth, development, and feedback to the environment have been isolated from the medicinal plants . These medicinal plants, since time immemorial, have been exploited as a source of novel pharmacophores in the production of lead compounds in the pharmaceutical industry. , …”

“… 4 These medicinal plants, since time immemorial, have been exploited as a source of novel pharmacophores in the production of lead compounds in the pharmaceutical industry. 5 , 6 …”