Medicinal plants and phytochemicals with anti-obesogenic potentials: A review

Mopuri, Ramgopal; Islam, Md. Shahidul

doi:10.1016/j.biopha.2017.02.108

Cited by 55 publications

(37 citation statements)

References 103 publications

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“…In the last decade, a huge number of plant extracts and their phytochemical constituents have been investigated to examine their potential anti-obesity effectiveness [83,84].…”

Section: Discussionmentioning

confidence: 99%

A Review of Biologically Active Natural Products from Mediterranean Wild Edible Plants: Benefits in the Treatment of Obesity and Its Related Disorders

2020

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Wild foods constitute an essential component of people’s diets around the world. According to the Food and Agriculture Organization (FAO), over 100 million people in the EU consume wild foods, while 65 million collect some form of wild food themselves. The Mediterranean basin is a biodiversity hotspot of wild edible species. Nowadays, due to the renewed interest in alimurgic plants and the recent findings on the beneficial role of their phytochemical constituents, these species have been defined as “new functional foods”. Research on natural products has recently regained importance with the growing understanding of their biological significance. Botanical food supplements marketed for weight and fat loss in obese subjects will be one of the most important items in marketed nutraceuticals. The aim of this report was to review the phytochemical compounds of Mediterranean wild edible species and their therapeutic potential against obesity and its related disorders. Results on the in vitro and in vivo activity of the most interesting plant extracts and their bioactive components are presented and discussed. The most interesting discoveries on their mechanisms of action are reported as well. Overall, this contribution highlights the importance and beneficial health roles of wild edible species.

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“…In the last decade, a huge number of plant extracts and their phytochemical constituents have been investigated to examine their potential anti-obesity effectiveness [83,84].…”

Section: Discussionmentioning

confidence: 99%

A Review of Biologically Active Natural Products from Mediterranean Wild Edible Plants: Benefits in the Treatment of Obesity and Its Related Disorders

2020

View full text Add to dashboard Cite

show abstract

“…The favorable effects of these antioxidant-rich foods on improvement of fasting blood glucose, lipid pro le and obesity have been investigated in some pre-clinical and clinical studies [49][50][51][52][53]. In recent years, chemical antioxidants, such as "phytochemicals", are suggested as plausible candidates in the prevention and/or treatment of speci c diseases, including obesity and obesity-related metabolic disorders [54].…”

Section: Discussionmentioning

confidence: 99%

Relationship between oxygen radical absorbance capacity (ORAC) index, body composition and blood biochemical markers in overweight /obese compared to normal weight subjects: a cross-sectional study

Madani

javardi

Djazayeri

et al. 2020

Preprint

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Background: Obesity is an important preventable disease, which promotes the development of chronic disorders by altering several factors including oxidative stress. Dietary antioxidants protect the body against oxidative stress. The purpose of this study was to evaluate the potential association of oxygen radical absorbance capacity (ORAC) index with obesity and its associated features in adults.Methods: participants were divided in two groups of normal weight and overweight /obesity. General characteristics were registered and a 147-item food frequency questionnaire was completed. Thereafter, anthropometric measurements were conducted. Biochemical indices were obtained from science and Research branch of Islamic Azad University of Tehran, Iran. The amount of the dietary ORAC index was estimated using the data provided by the USDA Foods Table.Results: The results showed that there was a significant difference between the normal and overweight/obese groups in terms of body mass index (BMI) and waist-to-hip ratio (WHR) (P=0.0001). Participants with normal weight consumed more fruits and vegetables than another group. Also, the dietary ORAC index in normal individuals was higher than the case group, but there was not significant difference (P=0.352). There was also a significant inverse correlation between dietary ORAC and BMI and WHR, whereas a significant positive correlation between dietary ORAC and plasma HDL was observed (P<0.05).Conclusion: Our findings suggest that dietary antioxidants is inversely associated with BMI, fasting blood glucose, triglyceride, total Cholesterol and LDL in both groups. It seems that following a diet rich in antioxidants can counteract obesity and its associated comorbidities.

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“…The favorable effects of these antioxidant-rich foods on improvement of fasting blood glucose, lipid profile and obesity have been investigated in some pre-clinical and clinical studies [38][39][40][41][42]. In recent years, chemical antioxidants, such as "phytochemicals", are suggested as plausible candidates in the prevention and/or treatment of specific diseases, including obesity and obesity-related metabolic disorders [43].…”

Section: Previous Studies Have Shown An Inverse Relationship Between mentioning

confidence: 99%

Relationship Between Oxygen Radical Absorbance Capacity (ORAC) Index, Body Composition and Blood Biochemical Markers in Overweight /Obese Compared to Normal Weight Subjects

Madani

Djazayery

et al. 2020

Preprint

View full text Add to dashboard Cite

Background and aim: Obesity is an important preventable disease, which promotes the development of multiple chronic disorders by altering several factors including oxidative stress. Dietary antioxidants protect the body against oxidative stress. The purpose of this study was to evaluate the potential association of oxygen radical absorbance capacity (ORAC) index with obesity and its associated biochemical factors in adults. Methods: The present study was a cross-sectional study of 157 adult females and males in two groups of normal weight and overweight /obesity. General characteristics were registered and a 147-item food frequency questionnaire was completed for every participant. Thereafter, anthropometric measurements were conducted. Biochemical indices were obtained from the Electronic Health Clinic Database of science and Research branch of Islamic Azad University (SRBIAU) of Tehran, Iran. The amount of the dietary ORAC index was estimated using the data provided by the USDA Foods Table. Results: The results showed that there was a significant difference between the normal and overweight/obese groups in terms of weight, body mass index (BMI), waist to hip ratio (WHR), visceral fat level, body fat mass and body fat percentage (P=0.0001). Participants with normal weight consumed more fruits and vegetables than individuals in another group. Also, the dietary ORAC index in normal individuals was higher than the case group, but there was not significant difference (P=0.222). There was also a significant inverse correlation between dietary ORAC and BMI and WHR, whereas a significant positive correlation between dietary ORAC and plasma levels of HDL was observed (P<0.05). Conclusion: Our findings suggest that consumption of antioxidants from dietary sources is inversely associated with BMI and other measurements of adiposity, fasting blood glucose (FBG), triglyceride (TG), total Cholesterol (TC) and LDL in both groups. It seems that following a diet rich in antioxidants can counteract obesity and its associated comorbidities.

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Medicinal plants and phytochemicals with anti-obesogenic potentials: A review

Cited by 55 publications

References 103 publications

A Review of Biologically Active Natural Products from Mediterranean Wild Edible Plants: Benefits in the Treatment of Obesity and Its Related Disorders

A Review of Biologically Active Natural Products from Mediterranean Wild Edible Plants: Benefits in the Treatment of Obesity and Its Related Disorders

Relationship between oxygen radical absorbance capacity (ORAC) index, body composition and blood biochemical markers in overweight /obese compared to normal weight subjects: a cross-sectional study

Relationship Between Oxygen Radical Absorbance Capacity (ORAC) Index, Body Composition and Blood Biochemical Markers in Overweight /Obese Compared to Normal Weight Subjects

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