Medicinal Applications of Cyanoacrylate

Pawar, Rajendra P.; Jadhav, Ashok E.; Tathe, Sumangala B.; Khade, Bhimrao C.; Domb, Abraham J.

doi:10.1002/9781118015810.ch12

Cited by 5 publications

(2 citation statements)

References 106 publications

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“…During application, the CA is exposed to anionic initiators (eg, hydroxyl groups or lone pairs of electrons on pendant NH 2 groups) on the surfaces being glued, inducing polymerization. 9,10 The polymer that forms has unique properties that better lend themselves to particular applications (Figure). The utility of the various CAs in the backcountry is directly related to their physical properties.…”

Section: Properties Of Cyanoacrylate Gluesmentioning

confidence: 99%

Cyanoacrylate Glues for Wilderness and Remote Travel Medical Care

Davis

Derlet

2013

Wilderness & Environmental Medicine

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Cyanoacrylate (CA) glues are commonly used in medical and household repairs. Their chemical compositions have been refined over half a century, making some more suitable than others for creative applications. In remote settings where advanced medical care is not accessible, readily available CAs of differing chemical composition may possess an important therapeutic function. Within this paper we critically examine the published therapeutic risks and benefits of both pharmaceutical and hardware grade CAs when applied in acute care situations. Topics discussed include wound closure as well as the treatment of burns, abrasions, and blisters. Also considered are their chemical properties, toxicities, and potential off-label uses.

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Section: Properties Of Cyanoacrylate Gluesmentioning

confidence: 99%

Cyanoacrylate Glues for Wilderness and Remote Travel Medical Care

Davis

Derlet

2013

Wilderness & Environmental Medicine

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“…Alkyl cyanoacrylates are solvent free liquids that polymerize and cure rapidly in the presence of nucleophiles (including moisture from the air) to form adhesive, glue, and films. , These alkyl cyanoacrylates have long been used for bonding nonporous materials in biomedical fields such as tissue adhesives, for drug delivery, in the automobile and electronics industries, and in forensic laboratories for fingerprint development. , Earlier generations of cyanoacrylates (methyl, ethyl) had significant performance limitations such as poor thermal stability, peel strength, and high tissue reaction. Continued research on cyanoacrylates resulted in the development of new alkyl cyanoacrylates to overcome these limitations.…”

Section: Introductionmentioning

confidence: 99%

Fluorescent Cyanoacrylate Monomers and Polymers for Fingermark Development

Bentolila¹,

Totre

Zozulia

et al. 2013

Macromolecules

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Cyanoacrylate esters with fluorescent side groups were synthesized and tested as agents for latent fingerprint development. Reactive monomers with benzyl, anthracyl, naphthyl, fluorenyl, propagyl, and cyanomethyl side groups were synthesized using the formation of an ethyl cyanoacrylate, anthracene adduct, followed by hydrolysis of the ethyl ester to the acid and esterification with a desired alcohol, and finally release of the monomer by retro-Diels−Alder with maleic anhydride. Monomers were prepared in high yield and purity as determined by spectral analysis. Attempts to synthesize these monomers from poly(ethyl cyanoacrylate) by transesterification and depolymerization resulted in low yields and low purity. The synthesized fluorescent monomers were found to be effective for latent fingerprint development in solution forming clear fluorescent fingerprint images suitable for forensic fingerprint comparison. These monomers can complement the current use of the commonly used nonfluorescent ethyl cyanoacrylate monomers for fingerprint development.

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Cyanoacrylate Adhesives

Raja

2017

Progress in Adhesion and Adhesives

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Medicinal Applications of Cyanoacrylate

Cited by 5 publications

References 106 publications

Cyanoacrylate Glues for Wilderness and Remote Travel Medical Care

Cyanoacrylate Glues for Wilderness and Remote Travel Medical Care

Fluorescent Cyanoacrylate Monomers and Polymers for Fingermark Development

Cyanoacrylate Adhesives

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