Medicinal and Therapeutic Potential of Herbs and Plant Metabolites / Extracts Countering Viral Pathogens - Current Knowledge and Future Prospects

Dhama, Kuldeep; Karthik, Kumaragurubaran; Khandia, Rekha; Munjal, Ashok; Tiwari, Ruchi; Rana, Rajneesh; Khurana, Sandip Kumar; Ullah, Sana; Khan, Rifat Ullah; Alagawany, Mahmoud; Farag, Mayada R.; Dadar, Maryam; Joshi, Sunil

doi:10.2174/1389200219666180129145252

Cited by 199 publications

(170 citation statements)

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“…Multiple beneficial health applications including the potent antimicrobial properties, medicinal and therapeutic values of Emblica officinalis need to be promoted and propagated with more researches and clinical trials, validation studies, promotional activities along with exploration of advances in biotechnology, pharmacology, pharmaceuticals, nanotechnology based approaches for developing effective drugs and medicines utilizing Amla 6, [15][16][17]24,75,139,[163][164][165] . Particularly, in the scenario of rising drug resistance, higher incidences of emerging and reemerging pathogenic microbes, the antimicrobial efficacy of Emblica officinalis can be exploited for important microbial pathogens including food-borne zoonotic bacteria such as Salmonella, Arcobacters, Camyplobacters, and emerging viral pathogens like Zika, Ebola, Nipah virus and others, so as to lessen their high incidences, devastating effects and public health effects; since various other herbs and plant metabolites / extracts have shown promising results against such pathogens 5,6,[166][167][168][169] .…”

Section: Other Potential Health Applications Of Amlamentioning

confidence: 99%

Emblica officinalis (Amla) with a Particular Focus on Its Antimicrobial Potentials: A Review

Khurana¹,

Tiwari²,

Sharun³

et al. 2019

J Pure Appl Microbiol

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Section: Other Potential Health Applications Of Amlamentioning

confidence: 99%

Emblica officinalis (Amla) with a Particular Focus on Its Antimicrobial Potentials: A Review

Khurana¹,

Tiwari²,

Sharun³

et al. 2019

J Pure Appl Microbiol

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“…In recent decades, plants' oils have been used routinely in chicken farms for keeping chickens healthy and enhancing their productive performance because they contain active components which exert positive effects on physiological processes and have medicinal effects such as antibacterial, anti-inflammatory, and antioxidant [7][8][9][10]. There is a global trend in restricting the use of antibiotic growth promoters in the animal diet [11] and finding alternative solutions to maintain current animal production efficiency.…”

Section: Introductionmentioning

confidence: 99%

Effect of Housing System and Rosemary and Cinnamon Essential Oils on Layers Performance, Egg Quality, Haematological Traits, Blood Chemistry, Immunity, and Antioxidant

Ghanima

Elsadek

Taha

et al. 2020

Animals

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Housing system and nutrition are non-genetic factors that can improve the well-being of animals to obtain higher quality products. A better understanding of how different housing systems and essential oils can influence the performance of layers is very important at the research and commercial levels. The current study aimed to investigate the effects of a housing system and dietary supplementation of rosemary and cinnamon essential oils on layers’ performance and egg quality. A factorial arrangement (2 × 3) was performed include two housing systems (floor and cage) and three different types of essential oils (0, 300 mg/kg diet of rosemary and 300 mg/kg diet of cinnamon essential oils) to study their effects on the productive performance, egg quality, immunity, oxidative stress and haematology of ISA brown laying hens during the production stages (from 28 to 76 weeks of age). Birds were randomly divided into two groups each comprising of 1500 birds; the first group was moved from the litter to reared laying cages while the second group was floor reared. Each group was randomly divided into three groups, the first was considered as a control group, the second treated with rosemary essential oil, and the third with cinnamon essential oil. The differences in egg production and weight, egg quality, feed intake and conversion, blood picture and chemistry, immunity, and antioxidant parameters between the different housing systems (floor and cage) were not significant at (p < 0.05 or 0.01). On the other hand, the egg production and weight, Haugh unit, feed intake and conversion, blood cholesterol, Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), urea, Ca, P, immunity, and antioxidant parameters were significantly (p < 0.05 or 0.01) better in rosemary and cinnamon groups than in the control group. Furthermore, the results of dietary supplementation with rosemary and cinnamon were very close. Regarding egg production and weight, there were no significant differences due to the interactions. The differences in egg mass among the interactions were also not significant except at 68–76 weeks, where the cage × cinnamon group was the highest. Under the floor rearing system, birds that were fed a diet supplemented with or without essential oils (EOs) consumed more feed than those raised under the cage system. Regarding feed conversion rate (FCR), the differences among the interactions were not significant except at 44–52, 52–60 and 68–76 weeks, where the cage × cinnamon group was the lowest. Excluding glutathione peroxidase (GPx) activity (p < 0.001), all immunity and antioxidant indices were not statistically different as a consequence of the interaction among EOs and housing systems. Additionally, the highest levels of phosphorus were observed for layers fed diets enriched with cinnamon oil with the cage or floor system. In conclusion, the data suggested that supplementation of rosemary and cinnamon essential oils in laying hen diet showed significantly positive effects on hen performance and egg production. Cholesterol, liver and kidney functions, immunity, and antioxidant parameters improved with rosemary and cinnamon supplementation when compared to the control. Additionally, the different housing systems did not result in any positive or negative impact on these traits.

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“…On the other hand, medicinal plants have been used in traditional medicine for centuries. That is why there is a general upsurge of interest in the application of plant extracts to prevent or treat manifold diseases [ 27 , 28 , 29 , 30 ]. It is known that some medicinal plants or their isolated chemical components (i.e., phytochemicals) are able to affect reproduction.…”

Section: Introductionmentioning

confidence: 99%

Abatement of the Stimulatory Effect of Copper Nanoparticles Supported on Titania on Ovarian Cell Functions by Some Plants and Phytochemicals

et al. 2020

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The application of nanoparticles has experienced a vertiginous growth, but their interaction with food and medicinal plants in organisms, especially in the control of reproduction, remains unresolved. We examined the influence of copper nanoparticles supported on titania (CuNPs/TiO2), plant extracts (buckwheat (Fagopyrum esculentum) and vitex (Vitex agnus-castus)), phytochemicals (rutin and apigenin), and their combination with CuNPs/TiO2 on ovarian cell functions, using cultured porcine ovarian granulosa cells. Cell viability, proliferation (PCNA accumulation), apoptosis (accumulation of bax), and hormones release (progesterone, testosterone, and 17β-estradiol) were analyzed by the Trypan blue test, quantitative immunocytochemistry, and ELISA, respectively. CuNPs/TiO2 increased cell viability, proliferation, apoptosis, and testosterone but not progesterone release, and reduced the 17β-estradiol output. Plant extracts and components have similar stimulatory action on ovarian cell functions as CuNPs/TiO2, but abated the majority of the CuNPs/TiO2 effects. This study concludes that (1) CuNPs/TiO2 can directly stimulate ovarian cell functions, promoting ovarian cell proliferation, apoptosis, turnover, viability, and steroid hormones release; (2) the plants buckwheat and vitex, as well as rutin and apigenin, can promote some of these ovarian functions too; and (3) these plant additives mitigate the CuNPs/TiO2’s activity, something that must be considered when applied together.

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Medicinal and Therapeutic Potential of Herbs and Plant Metabolites / Extracts Countering Viral Pathogens - Current Knowledge and Future Prospects

Cited by 199 publications

References 0 publications

Emblica officinalis (Amla) with a Particular Focus on Its Antimicrobial Potentials: A Review

Emblica officinalis (Amla) with a Particular Focus on Its Antimicrobial Potentials: A Review

Effect of Housing System and Rosemary and Cinnamon Essential Oils on Layers Performance, Egg Quality, Haematological Traits, Blood Chemistry, Immunity, and Antioxidant

Abatement of the Stimulatory Effect of Copper Nanoparticles Supported on Titania on Ovarian Cell Functions by Some Plants and Phytochemicals

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