Medicinal and Phytochemical Analysis of Alcoholic Whole Fruit Extracts of Actinidia Deliciosa

Abstract

Present study investigates antimicrobial, antioxidant activity and phytochemical profiling of alcoholic extracts of whole fruit of Actinidia deliciosa (kiwi fruit). Cold and hot extracts of whole Actinidia deliciosa fruit prepared in methanol and ethanol and their different concentrations were tested against common nosocomial infections and human pathogens of skin, gestrointestinal tract and upper respiratory tract. Extracts were evaluated for their phytochemical constituents and antioxidant activity. Cold ethanolic extract of whole kiwi fruit has good antimicrobial activity as it inhibited the growth of almost all test organisms at concentration less than 20 mg/ml. Cold ethanolic extract was also found to be effective against Candida albicans at a concentration of 38.33 mg/ml. Antioxidant activity was examined by DPPH radical scavenging assay, highest antioxidant activity was displayed by cold methanolic extract. The qualitative phytochemical analysis of the extracts revealed the presence of alkaloids, flavonoids, saponins, cardiac glycosides, tannins and terpenoids in whole fruit of Actinidia deliciosa.

Evaluation of the wound-healing potential of the kiwifruit extract by assessing its effects on human gingival fibroblasts and angiogenesis

“…17,21,22 Furthermore, the A. deliciosa extract acts against a wide spectrum of microorganisms, including Candida albicans, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica, and Salmonella typhi. 17,23 Moreover, the qualitative phytochemical analysis of the kiwifruit extract revealed the presence of carotenoids, alkaloids, flavonoids, saponins, tannins, and terpenoids, which shows its high antioxidant capacity. 23 Phytochemicals such as vitamin A, vitamin C and carotenoids are required for the synthesis of collagen, a fibrous protein that helps to reinforce connective tissues, which hold the structures of the body together.…”

“…17,23 Moreover, the qualitative phytochemical analysis of the kiwifruit extract revealed the presence of carotenoids, alkaloids, flavonoids, saponins, tannins, and terpenoids, which shows its high antioxidant capacity. 23 Phytochemicals such as vitamin A, vitamin C and carotenoids are required for the synthesis of collagen, a fibrous protein that helps to reinforce connective tissues, which hold the structures of the body together. They are also highly effective in protecting cells against damage by free radicals.…”

Anti-Asthmatic and Immunomodulatory Effect of Actinidia deliciosa Fruit on Swiss Albino Mice

“…This dried crude concentrate extract was weighed and stored in refrigerator at 4°C until needed for further practical use. 8…”

Preparation, Characterization, and Study of Complexes Containing Beta-lactam Group with Some Transitional Elements and their Biological Activity

“…Such Chelation improves the lipophilic character of the central metal atom, which subsequently favors its permeation through the cell membrane's lipid layer. The variation in the effectiveness of various compounds against different organisms depends either on the impermeability of the cells of the microbes or on differences in the ribosome of microbial cells [35,36].…”