Medication Use in Pregnancy; Treating the Mother: Protecting the Unborn

Gadot, Yifat; Koren, Gideon

doi:10.1007/978-3-319-12406-3_4

Cited by 1 publication

(1 citation statement)

References 216 publications

(197 reference statements)

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“…However, in contexts where there is more uncertainty, complexity (involving causal sequences) or ambiguity (where there may be multiple values and definitions of an 'unwanted outcome'), deeper levels of participatory engagement are required to enhance knowledge, legitimacy and thus impact [44,46]. Examples of these latter contexts include actions to minimise teratogenic risks of medicines [52].…”

Section: Conceptualising and Defining Engagementmentioning

confidence: 99%

‘Engagement’ of patients and healthcare professionals in regulatory pharmacovigilance: establishing a conceptual and methodological framework

Brown

Bahri

2019

Eur J Clin Pharmacol

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Background Engagement of patients and healthcare professionals is increasingly considered as fundamental to pharmacovigilance and risk minimisation activities. Few empirical studies of engagement exist and a lack of explicit conceptualisations impedes effective measurement, research and the development of evidence-based engagement interventions. Aims This article (1) develops a widely applicable conceptualisation, (2) considers various methodological challenges to researching engagement, proposing some solutions, and (3) outlines a basis for converting the conceptualisation into specific measures and indicators of engagement among stakeholders. Method We synthesise social science work on risk governance and public understandings of science with insights from studies in the pharmacovigilance field. Findings This leads us to define engagement as an ongoing process of knowledge exchange among stakeholders, with the adoption of this knowledge as the outcome which may feed back into engagement processes over time. We conceptualise this process via three dimensions; breadth, depth and texture. In addressing challenges to capturing each dimension, we emphasise the importance of combining survey approaches with qualitative studies and secondary data on medicines use, prescribing, adverse reaction reporting and health outcomes. A framework for evaluating engagement intervention processes and outcomes is proposed. Alongside measuring engagement via breadth and depth, we highlight the need to research the engagement process through attentiveness to texturewhat engagement feels like, what it means to people, and how this shapes motivations based on values, emotions, trust and rationales. Conclusion Capturing all three dimensions of engagement is vital to develop valid understandings of what works and why, thus informing engagement interventions of patients and healthcare professionals to given regulatory pharmacovigilance scenarios.

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Section: Conceptualising and Defining Engagementmentioning

confidence: 99%