Abstract:Poor adherence to prescribed medication regimens remains an important challenge preventing successful treatment of cardiovascular diseases such as hypertension. While studies have documented differences in the time of day or weekday vs weekend on medication adherence, no study has examined whether having a medication-taking routine contributes to increased medication adherence. The purpose of this study was to: (1) identify patients’ sociodemographic factors associated with consistent medication-taking routine… Show more
“…This finding was in line with those of studies done among Africa Americans (77.4%)28 and in northern Ethiopia (73.6%) 29. It was higher than those of studies done in the rural–urban slum areas of Hyderabad (60.6%),30 North India (57.2%),31 Congo-Brazzaville (67.5%),32 a tertiary hospital in Nigeria (44.7%),33 Tikur Anbessa Specialized Hospital in Addis Ababa (69.2%),23 and Adama Referral Hospital in Ethiopia (59.5%) 34.…”
BackgroundMedication adherence is an important predictor of optimal blood pressure control; hence, it significantly reduces the risk of cardiovascular disease (CVD) and associated deaths. However, studies on medication adherence and its associated factors are scarce. Thus, this study aimed to assess adherence to antihypertensive medications and identify associated factors at Debre Tabor General Hospital, northwest Ethiopia.MethodsA hospital-based cross-sectional study was conducted. Simple random sampling technique was used to select 346 participants. A structured questionnaire adapted from the World Health Organization (WHO) STEPwise approach was used to collect data. Medication adherence was measured by the four-item Morisky–Green–Levine Scale, with a score ≥3 defined as “good adherence”. Data were entered using Epi Info version 7 and exported to SPSS version 20 for analysis. Descriptive and summary statistics were used. Bivariate and multivariable analyses were also carried out.ResultsA total of 337 hypertensive patients participated in the study. Three-quarters (75.1%) of the participants were found to be adherent to their medication therapy. The multivariable logistic regression analysis showed that urban residence (adjusted odd ratio [AOR]=2.10, 95% confidence interval [CI]: 1.15, 3.85), taking less than two drugs per day (AOR=3.04, 95% CI: 1.53, 6.06), and having knowledge about hypertension (HTN) and its treatment (AOR=8.86, 95% CI: 4.67, 16.82) were positively and significantly associated with medication adherence, while age >60 years (AOR=0.33, 95% CI: 0.11, 0.98) was negatively and significantly associated with good medication adherence.ConclusionA significant proportion of hypertensive patients poorly adhere to antihypertensive medications. Age, residence, pill burden, and knowledge about HTN and its treatment are important predictors of medication adherence. Attention should be given to increase the knowledge of patients about their disease and its treatment, and due emphasis should also be given to older and rural patients.
“…This finding was in line with those of studies done among Africa Americans (77.4%)28 and in northern Ethiopia (73.6%) 29. It was higher than those of studies done in the rural–urban slum areas of Hyderabad (60.6%),30 North India (57.2%),31 Congo-Brazzaville (67.5%),32 a tertiary hospital in Nigeria (44.7%),33 Tikur Anbessa Specialized Hospital in Addis Ababa (69.2%),23 and Adama Referral Hospital in Ethiopia (59.5%) 34.…”
BackgroundMedication adherence is an important predictor of optimal blood pressure control; hence, it significantly reduces the risk of cardiovascular disease (CVD) and associated deaths. However, studies on medication adherence and its associated factors are scarce. Thus, this study aimed to assess adherence to antihypertensive medications and identify associated factors at Debre Tabor General Hospital, northwest Ethiopia.MethodsA hospital-based cross-sectional study was conducted. Simple random sampling technique was used to select 346 participants. A structured questionnaire adapted from the World Health Organization (WHO) STEPwise approach was used to collect data. Medication adherence was measured by the four-item Morisky–Green–Levine Scale, with a score ≥3 defined as “good adherence”. Data were entered using Epi Info version 7 and exported to SPSS version 20 for analysis. Descriptive and summary statistics were used. Bivariate and multivariable analyses were also carried out.ResultsA total of 337 hypertensive patients participated in the study. Three-quarters (75.1%) of the participants were found to be adherent to their medication therapy. The multivariable logistic regression analysis showed that urban residence (adjusted odd ratio [AOR]=2.10, 95% confidence interval [CI]: 1.15, 3.85), taking less than two drugs per day (AOR=3.04, 95% CI: 1.53, 6.06), and having knowledge about hypertension (HTN) and its treatment (AOR=8.86, 95% CI: 4.67, 16.82) were positively and significantly associated with medication adherence, while age >60 years (AOR=0.33, 95% CI: 0.11, 0.98) was negatively and significantly associated with good medication adherence.ConclusionA significant proportion of hypertensive patients poorly adhere to antihypertensive medications. Age, residence, pill burden, and knowledge about HTN and its treatment are important predictors of medication adherence. Attention should be given to increase the knowledge of patients about their disease and its treatment, and due emphasis should also be given to older and rural patients.
“…8,23,27 In these studies, an increase or decrease in the rate of adherence to the treatment with age may be due to the presence of comorbid chronic diseases, perceived health status, or differences in giving or receiving health care. 7,24 While gender is not a determinant for the rate of adherence to the pharmacological treatment in some studies the adherence rate is high in women in other studies. 8,19 In the present study, although not significant, the rate of adherence was high in women as in the literature.…”
Section: Discussionmentioning
confidence: 99%
“…Similarly, in some studies in the literature, adherence to pharmacological treatment is not associated with socio-demographic characteristics. 7,21,22,26 On the other hand, some studies have indicated that sociodemographic characteristics such as age, gender, level of education, perceived income status are related to adherence to the pharmacological treatment. 3,21,26 For example, while adherence to treatment increases in some studies as the age increases it decreases in other studies.…”
Section: Discussionmentioning
confidence: 99%
“…Rates of adherence to pharmacological treatment range between 52% and 87% in studies conducted in Turkey and between 48% and 84% in studies conducted abroad. 7,8,12,15,[19][20][21][22][23][24] The WHO has reported that rates of adherence to pharmacological treatment by hypertension patients vary between 20% and 80%. 25 Thus, it can be concluded that the rate of adherence to pharmacological treatment in this present study conducted in a semi-urban region in Turkey overlaps with the rates reported in the literature.…”
Section: Discussionmentioning
confidence: 99%
“…2,6 Several studies conducted in countries such as China, Taiwan, Ethiopia and India to assess patients' adherence to medication treatment by using different methods report that adherence rates vary between 48% and 86%, and that non-adherence both to pharmacological and to non-pharmacological treatment methods is the most important obstacle to blood pressure control. [7][8][9][10][11][12][13] Health personnel play a key role in patients' adherence to pharmacological and non-pharmacological treatment methods used for blood pressure control. It is possible to ensure patients' adherence to pharmacological and nonpharmacological treatment methods by monitoring the patient meticulously, determining the factors affecting patients' adherence to the treatment and planning attempts to eliminate these factors.…”
Background: The present study was aimed at determining hypertensive patients’ adherence to pharmacological and non-pharmacological treatment methods and factors affecting their adherence. Methods: This cross-sectional study was conducted with 418 patients aged 18 and over who met the inclusion criteria. Adherence to pharmacological and some non-pharmacological treatment methods is the dependent variable of the study. Data were collected using the personal information form, Morisky medication adherence scale. In the analysis, descriptive statistics, the chi square test, and logistic regression analysis were used. The significance level was accepted as p<0.05. Results: The rate of adherence to the pharmacological treatment was 78.2%. The rates of adherence to smoking cessation, diet and physical activity were 49.0%, 55.7% and 20.6% respectively. Age, employment status and perceived health status were associated with the adherence to smoking cessation; perceived income, resort to complementary alternative treatment methods and having regular controls (check-ups) were related to the adherence to the diet, and gender and perceived economic status were related to the adherence to physical activities (p<0.05). Conclusions: While approximately four out of five patients complied with the pharmacological treatment, rates of adherence to non-pharmacological treatment methods were low. Multidisciplinary intervention programs should be planned in order to regularly monitor patients at family health centers, to assess their adherence to treatment modalities and to promote adherence.
Medication adherence is defined as the degree to which a patient's behaviour corresponds to the agreed recommendations from a medical staff member. Good medication adherence is critical for maintaining the health of people, especially for chronic diseases (Asche et al., 2011;Han et al., 2014). Hypertension is a global public health problem, and it is the most important risk factor for all-cause mortality and disability worldwide (Collaborators, 2016). In 2010, hypertension was considered as a major risk factor for the global burden of disease (Lim et al., 2012). Studies have shown that controlled blood pressure may reduce 50% of cardiovascular events compared to uncontrolled blood pressure in people with hypertension (Kohlman-Trigoboff, 2016); thus, hypertension is a major modifiable risk factor
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